MAPK10 - Gene info - The Human Protein Atlas

MAPK10

TISSUE

SUBCELL

CELL LINE

CANCER

GENE INFORMATION

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Gene name	MAPK10 (HGNC Symbol)
Synonyms	JNK3, p493F12, p54bSAPK, PRKM10
Description	Mitogen-activated protein kinase 10 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with, and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4). Cyclin-dependent kianse 5 can phosphorylate, and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Chromosome	4
Cytoband	q21.3
Chromosome location (bp)	86015123 - 86594131
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000109339 (version 78.38)
Entrez gene	5602
UniProt	P53779 (UniProt - Evidence at protein level)
neXtProt	NX_P53779
Antibodypedia	MAPK10 antibodies

PROTEIN VIEW

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MAPK10-001		MAPK10-002		MAPK10-004		MAPK10-005		MAPK10-012		MAPK10-014		MAPK10-015		MAPK10-017		MAPK10-018		MAPK10-020		MAPK10-021		MAPK10-025		MAPK10-026		MAPK10-027		MAPK10-028		MAPK10-029		MAPK10-030		MAPK10-201		MAPK10-202

PROTEIN INFORMATION

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Splice variant	Ensembl	UniProt	Protein class	Gene ontology	Length (aa)	Molecular mass (kDa)	Signal peptide (predicted)	Transmembrane regions (predicted)
MAPK10-001	ENSP00000378598 ENST00000395169	P53779 Show all » « Hide P53779 [Direct mapping] Mitogen-activated protein kinase 10 A8MWW6 [Target identity:74%; Query identity:100%] MAPK10 protein {ECO:0000313\|EMBL:AAH65516.1}; Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000378586} B3KR72 [Target identity:49%; Query identity:100%] cDNA FLJ33785 fis, clone BRSSN2008125, highly similar to Mitogen-activated protein kinase 10 {ECO:0000313\|EMBL:BAG52284.1} D6R9C1 [Target identity:19%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000422985} D6RBH2 [Target identity:17%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000424128} D6RJF9 [Target identity:11%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000425654} D6RC26 [Target identity:7%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000423918}	Show » « Hide Enzymes ENZYME proteins Transferases Kinases CMGC Ser/Thr protein kinases MEMSAT-SVM predicted membrane proteins Predicted intracellular proteins RAS pathway related proteins Disease related genes Potential drug targets Protein evidence (Kim et al 2014)	Show » « Hide GO:0000165 [MAPK cascade] GO:0000187 [activation of MAPK activity] GO:0002224 [toll-like receptor signaling pathway] GO:0002755 [MyD88-dependent toll-like receptor signaling pathway] GO:0002756 [MyD88-independent toll-like receptor signaling pathway] GO:0004672 [protein kinase activity] GO:0004705 [JUN kinase activity] GO:0004707 [MAP kinase activity] GO:0004708 [MAP kinase kinase activity] GO:0004713 [protein tyrosine kinase activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0005739 [mitochondrion] GO:0005829 [cytosol] GO:0005886 [plasma membrane] GO:0006468 [protein phosphorylation] GO:0007165 [signal transduction] GO:0007254 [JNK cascade] GO:0007258 [JUN phosphorylation] GO:0008152 [metabolic process] GO:0009103 [lipopolysaccharide biosynthetic process] GO:0016020 [membrane] GO:0016772 [transferase activity, transferring phosphorus-containing groups] GO:0016773 [phosphotransferase activity, alcohol group as acceptor] GO:0034134 [toll-like receptor 2 signaling pathway] GO:0034138 [toll-like receptor 3 signaling pathway] GO:0034142 [toll-like receptor 4 signaling pathway] GO:0034146 [toll-like receptor 5 signaling pathway] GO:0034162 [toll-like receptor 9 signaling pathway] GO:0034166 [toll-like receptor 10 signaling pathway] GO:0035666 [TRIF-dependent toll-like receptor signaling pathway] GO:0038095 [Fc-epsilon receptor signaling pathway] GO:0038123 [toll-like receptor TLR1:TLR2 signaling pathway] GO:0038124 [toll-like receptor TLR6:TLR2 signaling pathway] GO:0045087 [innate immune response] GO:0051090 [regulation of sequence-specific DNA binding transcription factor activity] GO:0051403 [stress-activated MAPK cascade]	426	48.1	No	0
MAPK10-002	ENSP00000378595 ENST00000395166	P53779 Show all » « Hide P53779 [Direct mapping] Mitogen-activated protein kinase 10 A8MWW6 [Target identity:74%; Query identity:100%] MAPK10 protein {ECO:0000313\|EMBL:AAH65516.1}; Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000378586} B3KR72 [Target identity:49%; Query identity:100%] cDNA FLJ33785 fis, clone BRSSN2008125, highly similar to Mitogen-activated protein kinase 10 {ECO:0000313\|EMBL:BAG52284.1} D6R9C1 [Target identity:19%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000422985} D6RBH2 [Target identity:17%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000424128} D6RJF9 [Target identity:11%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000425654} D6RC26 [Target identity:7%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000423918}	Show » « Hide Enzymes ENZYME proteins Transferases Kinases CMGC Ser/Thr protein kinases MEMSAT-SVM predicted membrane proteins Predicted intracellular proteins RAS pathway related proteins Disease related genes Potential drug targets Protein evidence (Kim et al 2014)	Show » « Hide GO:0000165 [MAPK cascade] GO:0000187 [activation of MAPK activity] GO:0002224 [toll-like receptor signaling pathway] GO:0002755 [MyD88-dependent toll-like receptor signaling pathway] GO:0002756 [MyD88-independent toll-like receptor signaling pathway] GO:0004672 [protein kinase activity] GO:0004705 [JUN kinase activity] GO:0004707 [MAP kinase activity] GO:0004708 [MAP kinase kinase activity] GO:0004713 [protein tyrosine kinase activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0005739 [mitochondrion] GO:0005829 [cytosol] GO:0005886 [plasma membrane] GO:0006468 [protein phosphorylation] GO:0007165 [signal transduction] GO:0007254 [JNK cascade] GO:0007258 [JUN phosphorylation] GO:0008152 [metabolic process] GO:0009103 [lipopolysaccharide biosynthetic process] GO:0016020 [membrane] GO:0016772 [transferase activity, transferring phosphorus-containing groups] GO:0016773 [phosphotransferase activity, alcohol group as acceptor] GO:0034134 [toll-like receptor 2 signaling pathway] GO:0034138 [toll-like receptor 3 signaling pathway] GO:0034142 [toll-like receptor 4 signaling pathway] GO:0034146 [toll-like receptor 5 signaling pathway] GO:0034162 [toll-like receptor 9 signaling pathway] GO:0034166 [toll-like receptor 10 signaling pathway] GO:0035666 [TRIF-dependent toll-like receptor signaling pathway] GO:0038095 [Fc-epsilon receptor signaling pathway] GO:0038123 [toll-like receptor TLR1:TLR2 signaling pathway] GO:0038124 [toll-like receptor TLR6:TLR2 signaling pathway] GO:0045087 [innate immune response] GO:0051090 [regulation of sequence-specific DNA binding transcription factor activity] GO:0051403 [stress-activated MAPK cascade]	426	48.1	No	0
MAPK10-004	ENSP00000378589 ENST00000395160	P53779 Show all » « Hide P53779 [Direct mapping] Mitogen-activated protein kinase 10	Show » « Hide Enzymes ENZYME proteins Transferases Kinases CMGC Ser/Thr protein kinases MEMSAT-SVM predicted membrane proteins Predicted intracellular proteins RAS pathway related proteins Disease related genes Potential drug targets Protein evidence (Kim et al 2014)	Show » « Hide GO:0000187 [activation of MAPK activity] GO:0002224 [toll-like receptor signaling pathway] GO:0002755 [MyD88-dependent toll-like receptor signaling pathway] GO:0002756 [MyD88-independent toll-like receptor signaling pathway] GO:0004672 [protein kinase activity] GO:0004705 [JUN kinase activity] GO:0004708 [MAP kinase kinase activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0005739 [mitochondrion] GO:0005829 [cytosol] GO:0005886 [plasma membrane] GO:0006468 [protein phosphorylation] GO:0007165 [signal transduction] GO:0007254 [JNK cascade] GO:0007258 [JUN phosphorylation] GO:0016772 [transferase activity, transferring phosphorus-containing groups] GO:0034134 [toll-like receptor 2 signaling pathway] GO:0034138 [toll-like receptor 3 signaling pathway] GO:0034142 [toll-like receptor 4 signaling pathway] GO:0034146 [toll-like receptor 5 signaling pathway] GO:0034162 [toll-like receptor 9 signaling pathway] GO:0034166 [toll-like receptor 10 signaling pathway] GO:0035666 [TRIF-dependent toll-like receptor signaling pathway] GO:0038095 [Fc-epsilon receptor signaling pathway] GO:0038123 [toll-like receptor TLR1:TLR2 signaling pathway] GO:0038124 [toll-like receptor TLR6:TLR2 signaling pathway] GO:0045087 [innate immune response] GO:0051090 [regulation of sequence-specific DNA binding transcription factor activity] GO:0051403 [stress-activated MAPK cascade]	277	31.9	No	0
MAPK10-005	ENSP00000355297 ENST00000361569	P53779 Show all » « Hide P53779 [Direct mapping] Mitogen-activated protein kinase 10 D6RAU3 [Target identity:33%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000424755} D6RCB1 [Target identity:28%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000422277} D6RAJ0 [Target identity:27%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000421762} D6RFZ7 [Target identity:21%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000421359} D6R9C1 [Target identity:19%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000422985} D6RBH2 [Target identity:17%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000424128} D6RJF9 [Target identity:12%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000425654} D6RDG1 [Target identity:11%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000420987} D6RFX8 [Target identity:11%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000421409} D6RC26 [Target identity:7%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000423918}	Show » « Hide Enzymes ENZYME proteins Transferases Kinases CMGC Ser/Thr protein kinases MEMSAT-SVM predicted membrane proteins Predicted intracellular proteins RAS pathway related proteins Disease related genes Potential drug targets Protein evidence (Kim et al 2014)	Show » « Hide GO:0000187 [activation of MAPK activity] GO:0002224 [toll-like receptor signaling pathway] GO:0002755 [MyD88-dependent toll-like receptor signaling pathway] GO:0002756 [MyD88-independent toll-like receptor signaling pathway] GO:0004672 [protein kinase activity] GO:0004705 [JUN kinase activity] GO:0004708 [MAP kinase kinase activity] GO:0004713 [protein tyrosine kinase activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0005739 [mitochondrion] GO:0005829 [cytosol] GO:0005886 [plasma membrane] GO:0006468 [protein phosphorylation] GO:0007165 [signal transduction] GO:0007254 [JNK cascade] GO:0007258 [JUN phosphorylation] GO:0008152 [metabolic process] GO:0009103 [lipopolysaccharide biosynthetic process] GO:0016020 [membrane] GO:0016772 [transferase activity, transferring phosphorus-containing groups] GO:0016773 [phosphotransferase activity, alcohol group as acceptor] GO:0034134 [toll-like receptor 2 signaling pathway] GO:0034138 [toll-like receptor 3 signaling pathway] GO:0034142 [toll-like receptor 4 signaling pathway] GO:0034146 [toll-like receptor 5 signaling pathway] GO:0034162 [toll-like receptor 9 signaling pathway] GO:0034166 [toll-like receptor 10 signaling pathway] GO:0035666 [TRIF-dependent toll-like receptor signaling pathway] GO:0038095 [Fc-epsilon receptor signaling pathway] GO:0038123 [toll-like receptor TLR1:TLR2 signaling pathway] GO:0038124 [toll-like receptor TLR6:TLR2 signaling pathway] GO:0045087 [innate immune response] GO:0051090 [regulation of sequence-specific DNA binding transcription factor activity] GO:0051403 [stress-activated MAPK cascade]	422	48.6	No	0
MAPK10-012	ENSP00000352157 ENST00000359221	P53779 Show all » « Hide P53779 [Direct mapping] Mitogen-activated protein kinase 10 A8MWW6 [Target identity:68%; Query identity:100%] MAPK10 protein {ECO:0000313\|EMBL:AAH65516.1}; Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000378586} B3KR72 [Target identity:45%; Query identity:100%] cDNA FLJ33785 fis, clone BRSSN2008125, highly similar to Mitogen-activated protein kinase 10 {ECO:0000313\|EMBL:BAG52284.1} D6RAU3 [Target identity:30%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000424755} D6RCB1 [Target identity:26%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000422277} D6RAJ0 [Target identity:25%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000421762} D6RFZ7 [Target identity:19%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000421359} D6R9C1 [Target identity:18%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000422985} D6RBH2 [Target identity:15%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000424128} D6RDG1 [Target identity:10%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000420987} D6RFX8 [Target identity:10%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000421409} D6RJF9 [Target identity:10%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000425654} D6RC26 [Target identity:7%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000423918}	Show » « Hide Enzymes ENZYME proteins Transferases Kinases CMGC Ser/Thr protein kinases MEMSAT-SVM predicted membrane proteins Predicted intracellular proteins RAS pathway related proteins Disease related genes Potential drug targets Protein evidence (Kim et al 2014)	Show » « Hide GO:0000165 [MAPK cascade] GO:0000187 [activation of MAPK activity] GO:0002224 [toll-like receptor signaling pathway] GO:0002755 [MyD88-dependent toll-like receptor signaling pathway] GO:0002756 [MyD88-independent toll-like receptor signaling pathway] GO:0004672 [protein kinase activity] GO:0004705 [JUN kinase activity] GO:0004707 [MAP kinase activity] GO:0004708 [MAP kinase kinase activity] GO:0004713 [protein tyrosine kinase activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0005739 [mitochondrion] GO:0005829 [cytosol] GO:0005886 [plasma membrane] GO:0006468 [protein phosphorylation] GO:0007165 [signal transduction] GO:0007254 [JNK cascade] GO:0007258 [JUN phosphorylation] GO:0008152 [metabolic process] GO:0009103 [lipopolysaccharide biosynthetic process] GO:0016020 [membrane] GO:0016772 [transferase activity, transferring phosphorus-containing groups] GO:0016773 [phosphotransferase activity, alcohol group as acceptor] GO:0034134 [toll-like receptor 2 signaling pathway] GO:0034138 [toll-like receptor 3 signaling pathway] GO:0034142 [toll-like receptor 4 signaling pathway] GO:0034146 [toll-like receptor 5 signaling pathway] GO:0034162 [toll-like receptor 9 signaling pathway] GO:0034166 [toll-like receptor 10 signaling pathway] GO:0035666 [TRIF-dependent toll-like receptor signaling pathway] GO:0038095 [Fc-epsilon receptor signaling pathway] GO:0038123 [toll-like receptor TLR1:TLR2 signaling pathway] GO:0038124 [toll-like receptor TLR6:TLR2 signaling pathway] GO:0045087 [innate immune response] GO:0051090 [regulation of sequence-specific DNA binding transcription factor activity] GO:0051403 [stress-activated MAPK cascade]	464	52.6	No	0
MAPK10-014	ENSP00000378586 ENST00000395157	A8MWW6 Show all » « Hide A8MWW6 [Target identity:100%; Query identity:100%] MAPK10 protein {ECO:0000313\|EMBL:AAH65516.1}; Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000378586} B3KR72 [Target identity:66%; Query identity:100%] cDNA FLJ33785 fis, clone BRSSN2008125, highly similar to Mitogen-activated protein kinase 10 {ECO:0000313\|EMBL:BAG52284.1}	Show » « Hide MEMSAT-SVM predicted membrane proteins Predicted intracellular proteins RAS pathway related proteins Protein evidence (Kim et al 2014)	Show » « Hide GO:0000165 [MAPK cascade] GO:0004672 [protein kinase activity] GO:0004707 [MAP kinase activity] GO:0005524 [ATP binding] GO:0006468 [protein phosphorylation] GO:0016772 [transferase activity, transferring phosphorus-containing groups]	319	36	No	0
MAPK10-015	ENSP00000424154 ENST00000515400	B7Z1Z1 Show all » « Hide B7Z1Z1 [Target identity:91%; Query identity:100%] cDNA FLJ54598, highly similar to Mitogen-activated protein kinase 10 {ECO:0000313\|EMBL:BAH11677.1}	Show » « Hide MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins RAS pathway related proteins Protein evidence (Kim et al 2014)	Show » « Hide GO:0004672 [protein kinase activity] GO:0004713 [protein tyrosine kinase activity] GO:0005524 [ATP binding] GO:0006468 [protein phosphorylation] GO:0009103 [lipopolysaccharide biosynthetic process] GO:0016020 [membrane] GO:0016772 [transferase activity, transferring phosphorus-containing groups] GO:0016773 [phosphotransferase activity, alcohol group as acceptor]	335	38.4	No	0
MAPK10-017	ENSP00000420987 ENST00000513186	D6RDG1 Show all » « Hide D6RDG1 [Target identity:100%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000420987}	Show » « Hide Predicted intracellular proteins RAS pathway related proteins Protein evidence (Kim et al 2014)		48	5.6	No	0
MAPK10-018	ENSP00000423918 ENST00000502302	D6RC26 Show all » « Hide D6RC26 [Target identity:100%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000423918}	Show » « Hide Predicted intracellular proteins RAS pathway related proteins Protein evidence (Kim et al 2014)		33	3.8	No	0
MAPK10-020	ENSP00000421409 ENST00000503911	D6RFX8 Show all » « Hide D6RFX8 [Target identity:98%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000421409} D6RDG1 [Target identity:94%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000420987}	Show » « Hide Predicted intracellular proteins RAS pathway related proteins Protein evidence (Kim et al 2014)		51	6	No	0
MAPK10-021	ENSP00000421762 ENST00000511328	D6RAJ0 Show all » « Hide D6RAJ0 [Target identity:100%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000421762} D6RFZ7 [Target identity:77%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000421359} D6RBH2 [Target identity:62%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000424128} D6RJF9 [Target identity:43%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000425654} D6RFX8 [Target identity:42%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000421409} D6RDG1 [Target identity:41%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000420987} D6RC26 [Target identity:28%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000423918}	Show » « Hide Predicted intracellular proteins RAS pathway related proteins Protein evidence (Kim et al 2014)	Show » « Hide GO:0004672 [protein kinase activity] GO:0005524 [ATP binding] GO:0006468 [protein phosphorylation] GO:0008152 [metabolic process] GO:0016772 [transferase activity, transferring phosphorus-containing groups]	117	13.4	No	0
MAPK10-025	ENSP00000425654 ENST00000512689	D6RJF9 Show all » « Hide D6RJF9 [Target identity:98%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000425654} D6RC26 [Target identity:63%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000423918}	Show » « Hide Predicted intracellular proteins RAS pathway related proteins Protein evidence (Kim et al 2014)	Show » « Hide GO:0008152 [metabolic process] GO:0016772 [transferase activity, transferring phosphorus-containing groups]	52	5.7	No	0
MAPK10-026	ENSP00000421359 ENST00000506773	D6RFZ7 Show all » « Hide D6RFZ7 [Target identity:100%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000421359} D6RJF9 [Target identity:56%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000425654} D6RFX8 [Target identity:54%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000421409} D6RDG1 [Target identity:52%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000420987} D6RC26 [Target identity:36%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000423918}	Show » « Hide Predicted intracellular proteins RAS pathway related proteins Protein evidence (Kim et al 2014)	Show » « Hide GO:0008152 [metabolic process] GO:0016772 [transferase activity, transferring phosphorus-containing groups]	91	10.2	No	0
MAPK10-027	ENSP00000424755 ENST00000512017	D6RAU3 Show all » « Hide D6RAU3 [Target identity:100%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000424755} D6RCB1 [Target identity:85%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000422277} D6RAJ0 [Target identity:82%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000421762} D6RFZ7 [Target identity:64%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000421359} D6R9C1 [Target identity:59%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000422985} D6RBH2 [Target identity:51%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000424128} D6RJF9 [Target identity:36%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000425654} D6RFX8 [Target identity:35%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000421409} D6RDG1 [Target identity:34%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000420987} D6RC26 [Target identity:23%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000423918}	Show » « Hide Predicted intracellular proteins RAS pathway related proteins Protein evidence (Kim et al 2014)	Show » « Hide GO:0004672 [protein kinase activity] GO:0005524 [ATP binding] GO:0006468 [protein phosphorylation] GO:0008152 [metabolic process] GO:0016772 [transferase activity, transferring phosphorus-containing groups]	141	16.2	No	0
MAPK10-028	ENSP00000422985 ENST00000512564	D6R9C1 Show all » « Hide D6R9C1 [Target identity:100%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000422985} D6RBH2 [Target identity:86%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000424128} D6RJF9 [Target identity:60%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000425654} D6RC26 [Target identity:39%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000423918}	Show » « Hide Predicted intracellular proteins RAS pathway related proteins Protein evidence (Kim et al 2014)	Show » « Hide GO:0004672 [protein kinase activity] GO:0005524 [ATP binding] GO:0006468 [protein phosphorylation] GO:0008152 [metabolic process] GO:0016772 [transferase activity, transferring phosphorus-containing groups]	84	9.5	No	0
MAPK10-029	ENSP00000422277 ENST00000511167	D6RCB1 Show all » « Hide D6RCB1 [Target identity:100%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000422277} D6RAJ0 [Target identity:96%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000421762} D6RFZ7 [Target identity:75%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000421359} D6RBH2 [Target identity:60%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000424128} D6RJF9 [Target identity:42%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000425654} D6RFX8 [Target identity:41%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000421409} D6RDG1 [Target identity:39%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000420987} D6RC26 [Target identity:27%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000423918}	Show » « Hide Predicted intracellular proteins RAS pathway related proteins Protein evidence (Kim et al 2014)	Show » « Hide GO:0004672 [protein kinase activity] GO:0005524 [ATP binding] GO:0006468 [protein phosphorylation] GO:0008152 [metabolic process] GO:0016772 [transferase activity, transferring phosphorus-containing groups]	121	13.8	No	0
MAPK10-030	ENSP00000424128 ENST00000509464	D6RBH2 Show all » « Hide D6RBH2 [Target identity:98%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000424128} D6RJF9 [Target identity:68%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000425654} D6RC26 [Target identity:44%; Query identity:100%] Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000423918}	Show » « Hide Predicted intracellular proteins RAS pathway related proteins Protein evidence (Kim et al 2014)	Show » « Hide GO:0004672 [protein kinase activity] GO:0005524 [ATP binding] GO:0006468 [protein phosphorylation] GO:0008152 [metabolic process] GO:0016772 [transferase activity, transferring phosphorus-containing groups]	74	8.3	No	0
MAPK10-201	ENSP00000378590 ENST00000395161	Q499Y8 Show all » « Hide Q499Y8 [Target identity:100%; Query identity:100%] MAPK10 protein {ECO:0000313\|EMBL:AAH51731.1}; Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000414469}	Show » « Hide MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins RAS pathway related proteins Protein evidence (Kim et al 2014)	Show » « Hide GO:0000165 [MAPK cascade] GO:0004672 [protein kinase activity] GO:0004707 [MAP kinase activity] GO:0005524 [ATP binding] GO:0006468 [protein phosphorylation] GO:0016772 [transferase activity, transferring phosphorus-containing groups]	319	35.7	No	0
MAPK10-202	ENSP00000414469 ENST00000449047	Q499Y8 Show all » « Hide Q499Y8 [Target identity:100%; Query identity:100%] MAPK10 protein {ECO:0000313\|EMBL:AAH51731.1}; Mitogen-activated protein kinase 10 {ECO:0000313\|Ensembl:ENSP00000414469}	Show » « Hide MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins RAS pathway related proteins Protein evidence (Kim et al 2014)	Show » « Hide GO:0000165 [MAPK cascade] GO:0004672 [protein kinase activity] GO:0004707 [MAP kinase activity] GO:0005524 [ATP binding] GO:0006468 [protein phosphorylation] GO:0016772 [transferase activity, transferring phosphorus-containing groups]	319	35.7	No	0

The Human Protein Atlas project is funded by the Knut & Alice Wallenberg foundation.