HGFAC

GENE INFORMATION

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Gene name

HGFAC (HGNC Symbol)

Synonyms

HGFA, HGFAP

Description

HGF activator (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the peptidase S1 protein family. The encoded protein is first synthesized as an inactive single-chain precursor before being activated to a heterodimeric form by endoproteolytic processing. It acts as serine protease that converts hepatocyte growth factor to the active form. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

Chromosome

4

Cytoband

p16.3

Chromosome location (bp)

3441887 - 3449495

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000109758 (version 78.38)

Entrez gene

3083

UniProt

Q04756 (UniProt - Evidence at protein level)

neXtProt

NX_Q04756

Antibodypedia

HGFAC antibodies
 

PROTEIN VIEW

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HGFAC-001
 
HGFAC-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HGFAC-001 ENSP00000372224
ENST00000382774
Q04756
Show all »
Show » Show » 655 70.7 Yes 0
HGFAC-004 ENSP00000421801
ENST00000511533
D6RAR4
Show all »
Show » Show » 662 71.5 Yes 0