UGDH

GENE INFORMATION

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Gene name

UGDH

Synonyms

Description

UDP-glucose 6-dehydrogenase (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]

Chromosome

4

Cytoband

p14

Chromosome location (bp)

39498755 - 39528311

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000109814 (version 78.38)

Entrez gene

7358

UniProt

O60701 (UniProt - Evidence at protein level)

neXtProt

NX_O60701

Antibodypedia

UGDH antibodies
 

PROTEIN VIEW

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UGDH-001
 
UGDH-002
 
UGDH-003
 
UGDH-004
 
UGDH-005
 
UGDH-006
 
UGDH-007
 
UGDH-009
 
UGDH-010
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

UGDH-001 ENSP00000319501
ENST00000316423
O60701
Show all »
Show » Show » 494 55 No 0
UGDH-002 ENSP00000426560
ENST00000507089
O60701
Show all »
Show » Show » 397 44.4 No 0
UGDH-003 ENSP00000422909
ENST00000501493
O60701
Show all »
Show » Show » 427 47.6 No 0
UGDH-004 ENSP00000421954
ENST00000515021
E7EV97
Show all »
Show » Show » 181 19.8 No 0
UGDH-005 ENSP00000421757
ENST00000506179
O60701
Show all »
Show » Show » 494 55 No 0
UGDH-006 ENSP00000427708
ENST00000510490
D6RHF4
Show all »
Show » Show » 53 5.8 No 0
UGDH-007 ENSP00000422603
ENST00000509391
E7ER83
Show all »
Show » Show » 130 14.3 No 0
UGDH-009 ENSP00000422565
ENST00000505698
E7ER95
Show all »
Show » Show » 85 9.3 No 0
UGDH-010 ENSP00000425834
ENST00000514106
E7ETF4
Show all »
Show » Show » 153 16.8 No 0