P2RX3

GENE INFORMATION

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Gene name

P2RX3 (HGNC Symbol)

Synonyms

P2X3

Description

Purinergic receptor P2X, ligand-gated ion channel, 3 (HGNC Symbol)

Entrez gene summary

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes. It is possible that the development of selective antagonists for this receptor may have a therapeutic potential in pain relief and in the treatment of disorders of urine storage. [provided by RefSeq, Jul 2008]

Chromosome

11

Cytoband

q12.1

Chromosome location (bp)

57338374 - 57370600

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000109991 (version 78.38)

Entrez gene

5024

UniProt

P56373 (UniProt - Evidence at transcript level)

neXtProt

NX_P56373

Antibodypedia

P2RX3 antibodies
 

PROTEIN VIEW

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P2RX3-001
 
P2RX3-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

P2RX3-001 ENSP00000263314
ENST00000263314
P56373
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Show » Show » 397 44.3 No 2
P2RX3-201 ENSP00000484614
ENST00000616487
H0YDR6
Show all »
Show » Show » 396 44.2 No 2