APOA5

GENE INFORMATION

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Gene name

APOA5 (HGNC Symbol)

Synonyms

APOA-V, RAP3

Description

Apolipoprotein A-V (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is an apolipoprotein that plays an important role in regulating the plasma triglyceride levels, a major risk factor for coronary artery disease. It is a component of high density lipoprotein and is highly similar to a rat protein that is upregulated in response to liver injury. Mutations in this gene have been associated with hypertriglyceridemia and hyperlipoproteinemia type 5. This gene is located proximal to the apolipoprotein gene cluster on chromosome 11q23. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Oct 2009]

Chromosome

11

Cytoband

q23.3

Chromosome location (bp)

116789367 - 116792420

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000110243 (version 78.38)

Entrez gene

116519

UniProt

Q6Q788 (UniProt - Evidence at protein level)

neXtProt

NX_Q6Q788

Antibodypedia

APOA5 antibodies
 

PROTEIN VIEW

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APOA5-001
 
APOA5-002
 
APOA5-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

APOA5-001 ENSP00000227665
ENST00000227665
Q6Q788
Show all »
Show » Show » 366 41.2 Yes 0
APOA5-002 ENSP00000399701
ENST00000433069
C9JZZ0
Show all »
Show » Show » 162 18.5 Yes 0
APOA5-201 ENSP00000445002
ENST00000542499
Q6Q788
Show all »
Show » Show » 366 41.2 Yes 0