UPK2

GENE INFORMATION

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Gene name

UPK2 (HGNC Symbol)

Synonyms

MGC138598, UP2, UPII

Description

Uroplakin 2 (HGNC Symbol)

Entrez gene summary

This gene encodes one of the proteins of the highly conserved urothelium-specific integral membrane proteins of the asymmetric unit membrane which forms urothelium apical plaques in mammals. The asymmetric unit membrane is believed to strengthen the urothelium by preventing cell rupture during bladder distention. The encoded protein is expressed in the peripheral blood of bladder cancer patients with transitional cell carcinomas.[provided by RefSeq, Sep 2009]

Chromosome

11

Cytoband

q23.3

Chromosome location (bp)

118925164 - 118958559

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000110375 (version 78.38)

Entrez gene

7379

UniProt

O00526 (UniProt - Evidence at transcript level)

neXtProt

NX_O00526

Antibodypedia

UPK2 antibodies
 

PROTEIN VIEW

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UPK2-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

UPK2-001 ENSP00000264031
ENST00000264031
O00526
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