LEPREL2

GENE INFORMATION

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Gene name

LEPREL2 (HGNC Symbol)

Synonyms

GRCB, HSU47926, P3H3

Description

Leprecan-like 2 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the leprecan family of proteoglycans, which function as collagen prolyl hydroxylases that are required for proper collagen biosynthesis, folding and assembly. This protein, like other family members, is thought to reside in the endoplasmic reticulum. Epigenetic inactivation of this gene is associated with breast and other cancers, suggesting that it may function as a tumor suppressor. [provided by RefSeq, Aug 2013]

Chromosome

12

Cytoband

p13.31

Chromosome location (bp)

6828410 - 6839851

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000110811 (version 78.38)

Entrez gene

10536

UniProt

Q8IVL6 (UniProt - Evidence at protein level)

neXtProt

NX_Q8IVL6

Antibodypedia

LEPREL2 antibodies
 

PROTEIN VIEW

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LEPREL2-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

LEPREL2-002 ENSP00000478600
ENST00000290510
Q8IVL6
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