CAMKK2

GENE INFORMATION

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Gene name

CAMKK2 (HGNC Symbol)

Synonyms

CAMKK, CAMKKB, KIAA0787, MGC15254

Description

Calcium/calmodulin-dependent protein kinase kinase 2, beta (HGNC Symbol)

Entrez gene summary

The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. The major isoform of this gene plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Protein products of this gene also phosphorylate AMP-activated protein kinase (AMPK). This gene has its strongest expression in the brain and influences signalling cascades involved with learning and memory, neuronal differentiation and migration, neurite outgrowth, and synapse formation. Alternative splicing results in multiple transcript variants encoding distinct isoforms. The identified isoforms differ in their ability to undergo autophosphorylation and to phosphorylate downstream kinases. [provided by RefSeq, Jul 2012]

Chromosome

12

Cytoband

q24.31

Chromosome location (bp)

121237691 - 121298308

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000110931 (version 78.38)

Entrez gene

10645

UniProt

Q96RR4 (UniProt - Evidence at protein level)

neXtProt

NX_Q96RR4

Antibodypedia

CAMKK2 antibodies
 

PROTEIN VIEW

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 « 
 
CAMKK2-001
 
CAMKK2-002
 
CAMKK2-003
 
CAMKK2-004
 
CAMKK2-005
 
CAMKK2-006
 
CAMKK2-008
 
CAMKK2-009
 
CAMKK2-010
 
CAMKK2-011
 
CAMKK2-012
 
CAMKK2-013
 
CAMKK2-014
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CAMKK2-001 ENSP00000312741
ENST00000324774
Q96RR4
Show all »
Show » Show » 588 64.7 No 1
CAMKK2-002 ENSP00000376265
ENST00000392473
F5H4I7
Show all »
Show » Show » 533 58.9 No 1
CAMKK2-003 ENSP00000388273
ENST00000446440
F5H4I7
Show all »
Show » Show » 490 54.1 No 1
CAMKK2-004 ENSP00000445944
ENST00000538733
A0A024RBQ3
Show all »
Show » Show » 498 54.8 No 1
CAMKK2-005 ENSP00000336634
ENST00000337174
A0A024RBP6
Show all »
Show » Show » 541 59.6 No 1
CAMKK2-006 ENSP00000321230
ENST00000347034
A0A024RBP8
Show all »
Show » Show » 545 60 No 1
CAMKK2-008 ENSP00000384600
ENST00000404169
Q96RR4
Show all »
Show » Show » 588 64.7 No 1
CAMKK2-009 ENSP00000388368
ENST00000412367
A0A024RBP6
Show all »
Show » Show » 541 59.6 No 1
CAMKK2-010 ENSP00000384591
ENST00000402834
Q96RR4
Show all »
Show » Show » 588 64.7 No 1
CAMKK2-011 ENSP00000376266
ENST00000392474
F5H4I7
Show all »
Show » Show » 556 61.4 No 1
CAMKK2-012 ENSP00000441352
ENST00000545538
F5GZ00
Show all »
Show » Show » 343 38.6 No 1
CAMKK2-013 ENSP00000444894
ENST00000543477
F5H4I7
Show all »
Show » Show » 125 12.9 No 0
CAMKK2-014 ENSP00000445400
ENST00000544485
F5H360
Show all »
Show » 87 9 No 0