GCNT2

GENE INFORMATION

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Gene name

GCNT2 (HGNC Symbol)

Synonyms

bA360O19.2, bA421M1.1, CCAT, GCNT5, IGNT, II, NACGT1, NAGCT1, ULG3

Description

Glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) (HGNC Symbol)

Entrez gene summary

This gene encodes the enzyme responsible for formation of the blood group I antigen. The i and I antigens are distinguished by linear and branched poly-N-acetyllactosaminoglycans, respectively. The encoded protein is the I-branching enzyme, a beta-1,6-N-acetylglucosaminyltransferase responsible for the conversion of fetal i antigen to adult I antigen in erythrocytes during embryonic development. Mutations in this gene have been associated with adult i blood group phenotype. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Chromosome

6

Cytoband

Chromosome location (bp)

10492223 - 10629368

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000111846 (version 78.38)

Entrez gene

2651

UniProt

Q06430 (UniProt - Evidence at transcript level), Q8N0V5 (UniProt - Evidence at transcript level), Q8NFS9 (UniProt - Evidence at transcript level)

neXtProt

NX_Q06430, NX_Q8N0V5, NX_Q8NFS9

Antibodypedia

GCNT2 antibodies
 

PROTEIN VIEW

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GCNT2-001
 
GCNT2-003
 
GCNT2-004
 
GCNT2-006
 
GCNT2-010
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GCNT2-001 ENSP00000314844
ENST00000316170
Q06430
Show all »
Show » Show » 400 45.9 No 0
GCNT2-003 ENSP00000368917
ENST00000379597
Q8N0V5
Show all »
Show » Show » 402 45.9 No 0
GCNT2-004 ENSP00000265012
ENST00000265012
Q8NFS9
Show all »
Show » Show » 402 46.5 No 0
GCNT2-006 ENSP00000419411
ENST00000495262
Q8N0V5
Show all »
Show » Show » 402 45.9 No 0
GCNT2-010 ENSP00000386321
ENST00000410107
B7ZBL3
Show all »
Show » 116 13.2 No 0