FANCE

GENE INFORMATION

? »

Gene name

FANCE (HGNC Symbol)

Synonyms

FACE, FAE

Description

Fanconi anemia, complementation group E (HGNC Symbol)

Entrez gene summary

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group E. [provided by RefSeq, Jul 2008]

Chromosome

6

Cytoband

p21.31

Chromosome location (bp)

35452361 - 35467103

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000112039 (version 78.38)

Entrez gene

2178

UniProt

Q9HB96 (UniProt - Evidence at protein level)

neXtProt

NX_Q9HB96

Antibodypedia

FANCE antibodies
 

PROTEIN VIEW

? »
 
 
 
FANCE-001
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FANCE-001 ENSP00000229769
ENST00000229769
Q9HB96
Show all »
Show » Show » 536 58.7 No 0