SLC22A2

GENE INFORMATION

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Gene name

SLC22A2 (HGNC Symbol)

Synonyms

OCT2

Description

Solute carrier family 22 (organic cation transporter), member 2 (HGNC Symbol)

Entrez gene summary

Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. It is found primarily in the kidney, where it may mediate the first step in cation reabsorption. [provided by RefSeq, Jul 2008]

Chromosome

6

Cytoband

q25.3

Chromosome location (bp)

160171061 - 160277638

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000112499 (version 78.38)

Entrez gene

6582

UniProt

O15244 (UniProt - Evidence at protein level)

neXtProt

NX_O15244

Antibodypedia

SLC22A2 antibodies
 

PROTEIN VIEW

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SLC22A2-001
 
SLC22A2-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SLC22A2-001 ENSP00000355920
ENST00000366953
O15244
Show all »
Show » Show » 555 62.6 No >9
SLC22A2-003 ENSP00000355919
ENST00000366952
Q5T7Q5
Show all »
Show » Show » 334 37.9 No 5