RASGRF2

GENE INFORMATION

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Gene name

RASGRF2 (HGNC Symbol)

Synonyms

GRF2, Ras-GRF2

Description

Ras protein-specific guanine nucleotide-releasing factor 2 (HGNC Symbol)

Entrez gene summary

RAS GTPases cycle between an inactive GDP-bound state and an active GTP-bound state. This gene encodes a calcium-regulated nucleotide exchange factor activating both RAS and RAS-related protein, RAC1, through the exchange of bound GDP for GTP, thereby, coordinating the signaling of distinct mitogen-activated protein kinase pathways. [provided by RefSeq, Oct 2011]

Chromosome

5

Cytoband

q14.1

Chromosome location (bp)

80960672 - 81230156

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000113319 (version 78.38)

Entrez gene

5924

UniProt

O14827 (UniProt - Evidence at protein level)

neXtProt

NX_O14827

Antibodypedia

RASGRF2 antibodies
 

PROTEIN VIEW

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RASGRF2-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

RASGRF2-001 ENSP00000265080
ENST00000265080
O14827
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