LNPEP

GENE INFORMATION

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Gene name

LNPEP (HGNC Symbol)

Synonyms

CAP, P-LAP, PLAP

Description

Leucyl/cystinyl aminopeptidase (HGNC Symbol)

Entrez gene summary

This gene encodes a zinc-dependent aminopeptidase that cleaves vasopressin, oxytocin, lys-bradykinin, met-enkephalin, dynorphin A and other peptide hormones. The protein can be secreted in maternal serum, reside in intracellular vesicles with the insulin-responsive glucose transporter GLUT4, or form a type II integral membrane glycoprotein. The protein catalyzes the final step in the conversion of angiotensinogen to angiotensin IV (AT4) and is also a receptor for AT4. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Chromosome

5

Cytoband

q15

Chromosome location (bp)

96935394 - 97037515

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000113441 (version 78.38)

Entrez gene

4012

UniProt

Q9UIQ6 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UIQ6

Antibodypedia

LNPEP antibodies
 

PROTEIN VIEW

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LNPEP-001
 
LNPEP-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

LNPEP-001 ENSP00000231368
ENST00000231368
Q9UIQ6
Show all »
Show » Show » 1025 117.3 No 1
LNPEP-002 ENSP00000379117
ENST00000395770
Q9UIQ6
Show all »
Show » Show » 1011 115.6 No 1