BCHE

GENE INFORMATION

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Gene name

BCHE (HGNC Symbol)

Synonyms

CHE1, CHE2, E1

Description

Butyrylcholinesterase (HGNC Symbol)

Entrez gene summary

Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage. [provided by RefSeq, Jul 2008]

Chromosome

3

Cytoband

q26.1

Chromosome location (bp)

165772904 - 165837472

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000114200 (version 78.38)

Entrez gene

590

UniProt

P06276 (UniProt - Evidence at protein level)

neXtProt

NX_P06276

Antibodypedia

BCHE antibodies
 

PROTEIN VIEW

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BCHE-001
 
BCHE-002
 
BCHE-005
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

BCHE-001 ENSP00000264381
ENST00000264381
P06276
Show all »
Show » Show » 602 68.4 Yes 0
BCHE-002 ENSP00000418325
ENST00000479451
H0Y885
Show all »
Show » 132 15.6 No 0
BCHE-005 ENSP00000418504
ENST00000488954
H7C4Y0
Show all »
Show » 120 13.6 No 0