FGF12

GENE INFORMATION

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Gene name

FGF12 (HGNC Symbol)

Synonyms

FGF12B, FHF1

Description

Fibroblast growth factor 12 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This growth factor lacks the N-terminal signal sequence present in most of the FGF family members, but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal. When transfected into mammalian cells, this protein accumulated in the nucleus, but was not secreted. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Chromosome

3

Cytoband

Chromosome location (bp)

192139395 - 192767764

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000114279 (version 78.38)

Entrez gene

2257

UniProt

P61328 (UniProt - Evidence at protein level)

neXtProt

NX_P61328

Antibodypedia

FGF12 antibodies
 

PROTEIN VIEW

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FGF12-001
 
FGF12-002
 
FGF12-005
 
FGF12-006
 
FGF12-007
 
FGF12-008
 
FGF12-009
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FGF12-001 ENSP00000413496
ENST00000454309
P61328
Show all »
Show » Show » 243 27.4 No 0
FGF12-002 ENSP00000393686
ENST00000445105
P61328
Show all »
Show » Show » 181 20.4 No 0
FGF12-005 ENSP00000395517
ENST00000418610
C9JIN3
Show all »
Show » Show » 107 12.2 No 0
FGF12-006 ENSP00000410125
ENST00000430714
C9JEN8
Show all »
Show » Show » 144 16.2 No 0
FGF12-007 ENSP00000412904
ENST00000448795
C9JUK8
Show all »
Show » Show » 141 16 No 0
FGF12-008 ENSP00000400948
ENST00000440901
H7C1L8
Show all »
Show » Show » 138 15.6 No 0
FGF12-009 ENSP00000397635
ENST00000450716
P61328
Show all »
Show » Show » 181 20.4 No 0