EIF4G1 - Gene info - The Human Protein Atlas

EIF4G1

TISSUE

SUBCELL

CELL LINE

CANCER

GENE INFORMATION

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Gene name	EIF4G1 (HGNC Symbol)
Synonyms	EIF4F, EIF4G, p220, PARK18
Description	Eukaryotic translation initiation factor 4 gamma, 1 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage. [provided by RefSeq, Aug 2010]
Chromosome	3
Cytoband	q27.1
Chromosome location (bp)	184314495 - 184335358
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000114867 (version 78.38)
Entrez gene	1981
UniProt	Q04637 (UniProt - Evidence at protein level)
neXtProt	NX_Q04637
Antibodypedia	EIF4G1 antibodies

PROTEIN VIEW

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EIF4G1-001		EIF4G1-003		EIF4G1-005		EIF4G1-006		EIF4G1-007		EIF4G1-008		EIF4G1-009		EIF4G1-010		EIF4G1-012		EIF4G1-013		EIF4G1-014		EIF4G1-015		EIF4G1-016		EIF4G1-020		EIF4G1-022		EIF4G1-023		EIF4G1-024		EIF4G1-027		EIF4G1-028		EIF4G1-029		EIF4G1-031		EIF4G1-037		EIF4G1-038		EIF4G1-039		EIF4G1-041		EIF4G1-201		EIF4G1-202

PROTEIN INFORMATION

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Splice variant	Ensembl	UniProt	Protein class	Gene ontology	Length (aa)	Molecular mass (kDa)	Signal peptide (predicted)
EIF4G1-001	ENSP00000343450 ENST00000342981	Q04637 Show all » « Hide Q04637 [Direct mapping] Eukaryotic translation initiation factor 4 gamma 1 E7EUU4 [Target identity:97%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000395974} E9PGM1 [Target identity:94%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000407682} E7EX73 [Target identity:89%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000399858} C9J2Z7 [Target identity:52%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000391412} Q96I65 [Target identity:40%; Query identity:100%] EIF4G1 protein {ECO:0000313\|EMBL:AAH07788.1}; Eukaryotic translation initiation factor 4 gamma, 1 {ECO:0000313\|EMBL:AAP35946.1} C9JWW9 [Target identity:17%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000399969} C9JSU8 [Target identity:10%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000409545} C9J556 [Target identity:8%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000411707} C9JWH7 [Target identity:7%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000407244} C9J987 [Target identity:5%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000411214} C9JIH5 [Target identity:5%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000415842}	Show » « Hide THUMBUP predicted membrane proteins Predicted intracellular proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay] GO:0000288 [nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay] GO:0000289 [nuclear-transcribed mRNA poly(A) tail shortening] GO:0003723 [RNA binding] GO:0003743 [translation initiation factor activity] GO:0005488 [binding] GO:0005515 [protein binding] GO:0005829 [cytosol] GO:0006412 [translation] GO:0006413 [translational initiation] GO:0006446 [regulation of translational initiation] GO:0008135 [translation factor activity, nucleic acid binding] GO:0008219 [cell death] GO:0008286 [insulin receptor signaling pathway] GO:0010467 [gene expression] GO:0016020 [membrane] GO:0016032 [viral process] GO:0016070 [RNA metabolic process] GO:0016071 [mRNA metabolic process] GO:0019221 [cytokine-mediated signaling pathway] GO:0044267 [cellular protein metabolic process] GO:0044822 [poly(A) RNA binding]	1600	175.6	No
EIF4G1-003	ENSP00000376320 ENST00000392537	Q04637 Show all » « Hide Q04637 [Direct mapping] Eukaryotic translation initiation factor 4 gamma 1 C9J6B6 [Target identity:50%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000398145} Q96I65 [Target identity:42%; Query identity:100%] EIF4G1 protein {ECO:0000313\|EMBL:AAH07788.1}; Eukaryotic translation initiation factor 4 gamma, 1 {ECO:0000313\|EMBL:AAP35946.1} C9JWW9 [Target identity:18%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000399969} C9JSU8 [Target identity:10%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000409545} C9J556 [Target identity:9%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000411707} C9JWH7 [Target identity:8%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000407244} C9J987 [Target identity:6%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000411214}	Show » « Hide THUMBUP predicted membrane proteins Predicted intracellular proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay] GO:0000288 [nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay] GO:0000289 [nuclear-transcribed mRNA poly(A) tail shortening] GO:0003723 [RNA binding] GO:0003743 [translation initiation factor activity] GO:0005488 [binding] GO:0005515 [protein binding] GO:0005829 [cytosol] GO:0006412 [translation] GO:0006413 [translational initiation] GO:0006446 [regulation of translational initiation] GO:0008135 [translation factor activity, nucleic acid binding] GO:0008219 [cell death] GO:0008286 [insulin receptor signaling pathway] GO:0010467 [gene expression] GO:0016020 [membrane] GO:0016032 [viral process] GO:0016070 [RNA metabolic process] GO:0016071 [mRNA metabolic process] GO:0019221 [cytokine-mediated signaling pathway] GO:0044267 [cellular protein metabolic process] GO:0044822 [poly(A) RNA binding]	1512	166.6	No
EIF4G1-005	ENSP00000403269 ENST00000426123	C9JF13 Show all » « Hide C9JF13 [Target identity:100%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000403269} C9J6B6 [Target identity:83%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000398145} C9JWW9 [Target identity:31%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000399969} C9JSU8 [Target identity:18%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000409545} C9J556 [Target identity:15%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000411707} C9JWH7 [Target identity:14%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000407244}	Show » « Hide Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0003723 [RNA binding] GO:0005488 [binding] GO:0005515 [protein binding]	903	98.2	No
EIF4G1-006	ENSP00000413159 ENST00000421110	C9K073 Show all » « Hide C9K073 [Target identity:100%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000413159} C9JWW9 [Target identity:32%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000399969} C9JSU8 [Target identity:18%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000409545} C9J556 [Target identity:16%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000411707} C9JWH7 [Target identity:14%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000407244} C9J987 [Target identity:10%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000411214}	Show » « Hide Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0003723 [RNA binding] GO:0005488 [binding] GO:0005515 [protein binding]	869	93.4	No
EIF4G1-007	ENSP00000316879 ENST00000346169	Q04637 Show all » « Hide Q04637 [Direct mapping] Eukaryotic translation initiation factor 4 gamma 1 C9J6B6 [Target identity:47%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000398145} Q96I65 [Target identity:40%; Query identity:100%] EIF4G1 protein {ECO:0000313\|EMBL:AAH07788.1}; Eukaryotic translation initiation factor 4 gamma, 1 {ECO:0000313\|EMBL:AAP35946.1} C9JWW9 [Target identity:17%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000399969} C9JSU8 [Target identity:10%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000409545} C9J556 [Target identity:8%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000411707} C9JWH7 [Target identity:7%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000407244} C9J987 [Target identity:5%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000411214} C9JIH5 [Target identity:5%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000415842}	Show » « Hide THUMBUP predicted membrane proteins Predicted intracellular proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay] GO:0000288 [nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay] GO:0000289 [nuclear-transcribed mRNA poly(A) tail shortening] GO:0003723 [RNA binding] GO:0003743 [translation initiation factor activity] GO:0005488 [binding] GO:0005515 [protein binding] GO:0005829 [cytosol] GO:0006412 [translation] GO:0006413 [translational initiation] GO:0006446 [regulation of translational initiation] GO:0008135 [translation factor activity, nucleic acid binding] GO:0008219 [cell death] GO:0008286 [insulin receptor signaling pathway] GO:0010467 [gene expression] GO:0016020 [membrane] GO:0016032 [viral process] GO:0016070 [RNA metabolic process] GO:0016071 [mRNA metabolic process] GO:0019221 [cytokine-mediated signaling pathway] GO:0044267 [cellular protein metabolic process] GO:0044822 [poly(A) RNA binding]	1599	175.5	No
EIF4G1-008	ENSP00000391412 ENST00000450424	C9J2Z7 Show all » « Hide C9J2Z7 [Target identity:99%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000391412} C9JWW9 [Target identity:34%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000399969} C9JSU8 [Target identity:19%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000409545} C9J556 [Target identity:17%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000411707} C9JWH7 [Target identity:15%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000407244} C9J987 [Target identity:11%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000411214} C9JIH5 [Target identity:10%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000415842}	Show » « Hide Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0003723 [RNA binding] GO:0005488 [binding] GO:0005515 [protein binding]	834	89.2	No
EIF4G1-009	ENSP00000317600 ENST00000350481	Q04637 Show all » « Hide Q04637 [Direct mapping] Eukaryotic translation initiation factor 4 gamma 1 C9J6B6 [Target identity:52%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000398145} Q96I65 [Target identity:44%; Query identity:100%] EIF4G1 protein {ECO:0000313\|EMBL:AAH07788.1}; Eukaryotic translation initiation factor 4 gamma, 1 {ECO:0000313\|EMBL:AAP35946.1} C9JWW9 [Target identity:19%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000399969} C9JSU8 [Target identity:11%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000409545} C9J556 [Target identity:9%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000411707} C9JWH7 [Target identity:8%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000407244}	Show » « Hide THUMBUP predicted membrane proteins Predicted intracellular proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay] GO:0000288 [nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay] GO:0000289 [nuclear-transcribed mRNA poly(A) tail shortening] GO:0003723 [RNA binding] GO:0003743 [translation initiation factor activity] GO:0005488 [binding] GO:0005515 [protein binding] GO:0005829 [cytosol] GO:0006412 [translation] GO:0006413 [translational initiation] GO:0006446 [regulation of translational initiation] GO:0008135 [translation factor activity, nucleic acid binding] GO:0008219 [cell death] GO:0008286 [insulin receptor signaling pathway] GO:0010467 [gene expression] GO:0016020 [membrane] GO:0016032 [viral process] GO:0016070 [RNA metabolic process] GO:0016071 [mRNA metabolic process] GO:0019221 [cytokine-mediated signaling pathway] GO:0044267 [cellular protein metabolic process] GO:0044822 [poly(A) RNA binding]	1435	158.5	No
EIF4G1-010	ENSP00000391935 ENST00000414031	Q04637 Show all » « Hide Q04637 [Direct mapping] Eukaryotic translation initiation factor 4 gamma 1 C9J6B6 [Target identity:48%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000398145} Q96I65 [Target identity:41%; Query identity:100%] EIF4G1 protein {ECO:0000313\|EMBL:AAH07788.1}; Eukaryotic translation initiation factor 4 gamma, 1 {ECO:0000313\|EMBL:AAP35946.1} C9JWW9 [Target identity:18%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000399969} C9JSU8 [Target identity:10%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000409545} C9J556 [Target identity:9%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000411707} C9JWH7 [Target identity:8%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000407244} C9J987 [Target identity:5%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000411214} C9JIH5 [Target identity:5%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000415842}	Show » « Hide THUMBUP predicted membrane proteins Predicted intracellular proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay] GO:0000288 [nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay] GO:0000289 [nuclear-transcribed mRNA poly(A) tail shortening] GO:0003723 [RNA binding] GO:0003743 [translation initiation factor activity] GO:0005488 [binding] GO:0005515 [protein binding] GO:0005829 [cytosol] GO:0006412 [translation] GO:0006413 [translational initiation] GO:0006446 [regulation of translational initiation] GO:0008135 [translation factor activity, nucleic acid binding] GO:0008219 [cell death] GO:0008286 [insulin receptor signaling pathway] GO:0010467 [gene expression] GO:0016020 [membrane] GO:0016032 [viral process] GO:0016070 [RNA metabolic process] GO:0016071 [mRNA metabolic process] GO:0019221 [cytokine-mediated signaling pathway] GO:0044267 [cellular protein metabolic process] GO:0044822 [poly(A) RNA binding]	1559	171.5	No
EIF4G1-012	ENSP00000407682 ENST00000427845	E9PGM1 Show all » « Hide E9PGM1 [Target identity:100%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000407682} E7EX73 [Target identity:94%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000399858} Q96I65 [Target identity:42%; Query identity:100%] EIF4G1 protein {ECO:0000313\|EMBL:AAH07788.1}; Eukaryotic translation initiation factor 4 gamma, 1 {ECO:0000313\|EMBL:AAP35946.1} C9JWW9 [Target identity:18%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000399969} C9JSU8 [Target identity:10%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000409545} C9J556 [Target identity:9%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000411707} C9JWH7 [Target identity:8%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000407244} C9J987 [Target identity:6%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000411214}	Show » « Hide THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0003723 [RNA binding] GO:0005488 [binding] GO:0005515 [protein binding]	1513	166.7	No
EIF4G1-013	ENSP00000416255 ENST00000424196	Q04637 Show all » « Hide Q04637 [Direct mapping] Eukaryotic translation initiation factor 4 gamma 1 C9J6B6 [Target identity:47%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000398145} Q96I65 [Target identity:40%; Query identity:100%] EIF4G1 protein {ECO:0000313\|EMBL:AAH07788.1}; Eukaryotic translation initiation factor 4 gamma, 1 {ECO:0000313\|EMBL:AAP35946.1} C9JWW9 [Target identity:17%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000399969} C9JSU8 [Target identity:10%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000409545} C9J556 [Target identity:8%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000411707} C9JWH7 [Target identity:7%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000407244} C9J987 [Target identity:5%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000411214}	Show » « Hide THUMBUP predicted membrane proteins Predicted intracellular proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay] GO:0000288 [nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay] GO:0000289 [nuclear-transcribed mRNA poly(A) tail shortening] GO:0003723 [RNA binding] GO:0003743 [translation initiation factor activity] GO:0005488 [binding] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0006412 [translation] GO:0006413 [translational initiation] GO:0006446 [regulation of translational initiation] GO:0008135 [translation factor activity, nucleic acid binding] GO:0008219 [cell death] GO:0008286 [insulin receptor signaling pathway] GO:0010467 [gene expression] GO:0016020 [membrane] GO:0016032 [viral process] GO:0016070 [RNA metabolic process] GO:0016071 [mRNA metabolic process] GO:0019221 [cytokine-mediated signaling pathway] GO:0044267 [cellular protein metabolic process] GO:0044822 [poly(A) RNA binding]	1606	176.2	No
EIF4G1-014	ENSP00000371767 ENST00000382330	Q04637 Show all » « Hide Q04637 [Direct mapping] Eukaryotic translation initiation factor 4 gamma 1 C9J6B6 [Target identity:47%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000398145} Q96I65 [Target identity:40%; Query identity:100%] EIF4G1 protein {ECO:0000313\|EMBL:AAH07788.1}; Eukaryotic translation initiation factor 4 gamma, 1 {ECO:0000313\|EMBL:AAP35946.1} C9JWW9 [Target identity:17%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000399969} C9JSU8 [Target identity:10%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000409545} C9J556 [Target identity:8%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000411707} C9JWH7 [Target identity:7%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000407244} C9J987 [Target identity:5%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000411214}	Show » « Hide THUMBUP predicted membrane proteins Predicted intracellular proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay] GO:0000288 [nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay] GO:0000289 [nuclear-transcribed mRNA poly(A) tail shortening] GO:0003723 [RNA binding] GO:0003743 [translation initiation factor activity] GO:0005488 [binding] GO:0005515 [protein binding] GO:0005829 [cytosol] GO:0006412 [translation] GO:0006413 [translational initiation] GO:0006446 [regulation of translational initiation] GO:0008135 [translation factor activity, nucleic acid binding] GO:0008219 [cell death] GO:0008286 [insulin receptor signaling pathway] GO:0010467 [gene expression] GO:0016020 [membrane] GO:0016032 [viral process] GO:0016070 [RNA metabolic process] GO:0016071 [mRNA metabolic process] GO:0019221 [cytokine-mediated signaling pathway] GO:0044267 [cellular protein metabolic process] GO:0044822 [poly(A) RNA binding]	1606	176.2	No
EIF4G1-015	ENSP00000398145 ENST00000444861	C9J6B6 Show all » « Hide C9J6B6 [Target identity:100%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000398145} C9JWW9 [Target identity:37%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000399969} C9JSU8 [Target identity:21%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000409545} C9J556 [Target identity:18%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000411707} C9JWH7 [Target identity:16%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000407244}	Show » « Hide Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0003723 [RNA binding] GO:0005488 [binding] GO:0005515 [protein binding]	757	82.5	No
EIF4G1-016	ENSP00000411826 ENST00000434061	Q04637 Show all » « Hide Q04637 [Direct mapping] Eukaryotic translation initiation factor 4 gamma 1 Q96I65 [Target identity:45%; Query identity:100%] EIF4G1 protein {ECO:0000313\|EMBL:AAH07788.1}; Eukaryotic translation initiation factor 4 gamma, 1 {ECO:0000313\|EMBL:AAP35946.1} C9JWW9 [Target identity:20%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000399969} C9JSU8 [Target identity:11%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000409545} C9J556 [Target identity:10%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000411707} C9JWH7 [Target identity:9%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000407244}	Show » « Hide THUMBUP predicted membrane proteins Predicted intracellular proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay] GO:0000288 [nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay] GO:0000289 [nuclear-transcribed mRNA poly(A) tail shortening] GO:0003723 [RNA binding] GO:0003743 [translation initiation factor activity] GO:0005488 [binding] GO:0005515 [protein binding] GO:0005829 [cytosol] GO:0006412 [translation] GO:0006413 [translational initiation] GO:0006446 [regulation of translational initiation] GO:0008135 [translation factor activity, nucleic acid binding] GO:0008219 [cell death] GO:0008286 [insulin receptor signaling pathway] GO:0010467 [gene expression] GO:0016020 [membrane] GO:0016032 [viral process] GO:0016070 [RNA metabolic process] GO:0016071 [mRNA metabolic process] GO:0019221 [cytokine-mediated signaling pathway] GO:0044267 [cellular protein metabolic process] GO:0044822 [poly(A) RNA binding]	1404	154.9	No
EIF4G1-020	ENSP00000415842 ENST00000455679	C9JIH5 Show all » « Hide C9JIH5 [Target identity:100%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000415842}	Show » « Hide Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)		87	9.2	No
EIF4G1-022	ENSP00000407240 ENST00000440448	C9JWH9 Show all » « Hide C9JWH9 [Target identity:99%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000407240}	Show » « Hide Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)		144	14.9	No
EIF4G1-023	ENSP00000411214 ENST00000427141	C9J987 Show all » « Hide C9J987 [Target identity:100%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000411214}	Show » « Hide Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)		92	9.9	No
EIF4G1-024	ENSP00000415943 ENST00000456033	C9JHW9 Show all » « Hide C9JHW9 [Target identity:100%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000415943}	Show » « Hide Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)		160	17	No
EIF4G1-027	ENSP00000411707 ENST00000428387	C9J556 Show all » « Hide C9J556 [Target identity:100%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000411707} C9JWH7 [Target identity:88%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000407244}	Show » « Hide Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)		143	14.8	No
EIF4G1-028	ENSP00000409545 ENST00000427607	C9JSU8 Show all » « Hide C9JSU8 [Target identity:100%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000409545} C9J556 [Target identity:87%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000411707} C9JWH7 [Target identity:77%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000407244}	Show » « Hide Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)		163	16.9	No
EIF4G1-029	ENSP00000399969 ENST00000457456	C9JWW9 Show all » « Hide C9JWW9 [Target identity:100%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000399969} C9JSU8 [Target identity:57%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000409545} C9J556 [Target identity:50%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000411707} C9JWH7 [Target identity:44%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000407244}	Show » « Hide Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)		285	29.3	No
EIF4G1-031	ENSP00000392908 ENST00000448284		Show » « Hide Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0003723 [RNA binding] GO:0005488 [binding] GO:0005515 [protein binding]	226	24.7	No
EIF4G1-037	ENSP00000407244 ENST00000444134	C9JWH7 Show all » « Hide C9JWH7 [Target identity:100%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000407244}	Show » « Hide Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)		127	13	No
EIF4G1-038	ENSP00000395974 ENST00000411531	E7EUU4 Show all » « Hide E7EUU4 [Target identity:100%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000395974} E9PGM1 [Target identity:96%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000407682} E7EX73 [Target identity:92%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000399858} Q96I65 [Target identity:41%; Query identity:100%] EIF4G1 protein {ECO:0000313\|EMBL:AAH07788.1}; Eukaryotic translation initiation factor 4 gamma, 1 {ECO:0000313\|EMBL:AAP35946.1} C9JWW9 [Target identity:18%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000399969} C9JSU8 [Target identity:10%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000409545} C9J556 [Target identity:9%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000411707} C9JWH7 [Target identity:8%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000407244} C9J987 [Target identity:5%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000411214} C9JIH5 [Target identity:5%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000415842}	Show » « Hide THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0003723 [RNA binding] GO:0005488 [binding] GO:0005515 [protein binding]	1560	171.6	No
EIF4G1-039	ENSP00000399858 ENST00000441154	E7EX73 Show all » « Hide E7EX73 [Target identity:100%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000399858} Q96I65 [Target identity:44%; Query identity:100%] EIF4G1 protein {ECO:0000313\|EMBL:AAH07788.1}; Eukaryotic translation initiation factor 4 gamma, 1 {ECO:0000313\|EMBL:AAP35946.1} C9JWW9 [Target identity:19%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000399969} C9JSU8 [Target identity:11%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000409545} C9J556 [Target identity:9%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000411707} C9JWH7 [Target identity:8%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000407244}	Show » « Hide THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0003723 [RNA binding] GO:0005488 [binding] GO:0005515 [protein binding]	1436	158.6	No
EIF4G1-041	ENSP00000404754 ENST00000435046	Q04637 Show all » « Hide Q04637 [Direct mapping] Eukaryotic translation initiation factor 4 gamma 1 Q96I65 [Target identity:45%; Query identity:100%] EIF4G1 protein {ECO:0000313\|EMBL:AAH07788.1}; Eukaryotic translation initiation factor 4 gamma, 1 {ECO:0000313\|EMBL:AAP35946.1} C9JWW9 [Target identity:20%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000399969} C9JSU8 [Target identity:11%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000409545} C9J556 [Target identity:10%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000411707} C9JWH7 [Target identity:9%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000407244}	Show » « Hide THUMBUP predicted membrane proteins Predicted intracellular proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay] GO:0000288 [nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay] GO:0000289 [nuclear-transcribed mRNA poly(A) tail shortening] GO:0003723 [RNA binding] GO:0003743 [translation initiation factor activity] GO:0005488 [binding] GO:0005515 [protein binding] GO:0005829 [cytosol] GO:0006412 [translation] GO:0006413 [translational initiation] GO:0006446 [regulation of translational initiation] GO:0008135 [translation factor activity, nucleic acid binding] GO:0008219 [cell death] GO:0008286 [insulin receptor signaling pathway] GO:0010467 [gene expression] GO:0016020 [membrane] GO:0016032 [viral process] GO:0016070 [RNA metabolic process] GO:0016071 [mRNA metabolic process] GO:0019221 [cytokine-mediated signaling pathway] GO:0044267 [cellular protein metabolic process] GO:0044822 [poly(A) RNA binding]	1403	154.8	No
EIF4G1-201	ENSP00000323737 ENST00000319274	C9JWW9 Show all » « Hide C9JWW9 [Target identity:20%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000399969} C9JSU8 [Target identity:11%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000409545} C9J556 [Target identity:10%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000411707} C9JWH7 [Target identity:9%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000407244}	Show » « Hide THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0003723 [RNA binding] GO:0005488 [binding] GO:0005515 [protein binding]	1395	153.2	No
EIF4G1-202	ENSP00000338020 ENST00000352767	Q04637 Show all » « Hide Q04637 [Direct mapping] Eukaryotic translation initiation factor 4 gamma 1 C9J6B6 [Target identity:47%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000398145} Q96I65 [Target identity:40%; Query identity:100%] EIF4G1 protein {ECO:0000313\|EMBL:AAH07788.1}; Eukaryotic translation initiation factor 4 gamma, 1 {ECO:0000313\|EMBL:AAP35946.1} C9JWW9 [Target identity:17%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000399969} C9JSU8 [Target identity:10%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000409545} C9J556 [Target identity:8%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000411707} C9JWH7 [Target identity:7%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000407244} C9J987 [Target identity:5%; Query identity:100%] Eukaryotic translation initiation factor 4 gamma 1 {ECO:0000313\|Ensembl:ENSP00000411214}	Show » « Hide THUMBUP predicted membrane proteins Predicted intracellular proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay] GO:0000288 [nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay] GO:0000289 [nuclear-transcribed mRNA poly(A) tail shortening] GO:0003723 [RNA binding] GO:0003743 [translation initiation factor activity] GO:0005488 [binding] GO:0005515 [protein binding] GO:0005829 [cytosol] GO:0006412 [translation] GO:0006413 [translational initiation] GO:0006446 [regulation of translational initiation] GO:0008135 [translation factor activity, nucleic acid binding] GO:0008219 [cell death] GO:0008286 [insulin receptor signaling pathway] GO:0010467 [gene expression] GO:0016020 [membrane] GO:0016032 [viral process] GO:0016070 [RNA metabolic process] GO:0016071 [mRNA metabolic process] GO:0019221 [cytokine-mediated signaling pathway] GO:0044267 [cellular protein metabolic process] GO:0044822 [poly(A) RNA binding]	1606	176.2	No

The Human Protein Atlas project is funded by the Knut & Alice Wallenberg foundation.