CENPA

GENE INFORMATION

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Gene name

CENPA (HGNC Symbol)

Synonyms

CenH3, CENP-A

Description

Centromere protein A (HGNC Symbol)

Entrez gene summary

Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]

Chromosome

2

Cytoband

p23.3

Chromosome location (bp)

26764289 - 26801067

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000115163 (version 78.38)

Entrez gene

1058

UniProt

P49450 (UniProt - Evidence at protein level)

neXtProt

NX_P49450

Antibodypedia

CENPA antibodies
 

PROTEIN VIEW

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CENPA-001
 
CENPA-006
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CENPA-001 ENSP00000336868
ENST00000335756
P49450
Show all »
Show » Show » 140 16 No 0
CENPA-006 ENSP00000233505
ENST00000233505
P49450
Show all »
Show » Show » 114 13 No 0