FN1 - Gene info - The Human Protein Atlas

FN1

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TISSUE

SUBCELL

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CELL LINE

CANCER

GENE INFORMATION

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Gene name	FN1 (HGNC Symbol)
Synonyms	CIG, FINC, GFND2, LETS, MSF
Description	Fibronectin 1 (HGNC Symbol)
Entrez gene summary	This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants. However, the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]
Chromosome	2
Cytoband	q35
Chromosome location (bp)	215360440 - 215436172
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000115414 (version 78.38)
Entrez gene	2335
UniProt	P02751 (UniProt - Evidence at protein level)
neXtProt	NX_P02751
Antibodypedia	FN1 antibodies

PROTEIN VIEW

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FN1-001		FN1-002		FN1-003		FN1-004		FN1-005		FN1-008		FN1-009		FN1-011		FN1-012		FN1-013		FN1-014		FN1-026		FN1-201

PROTEIN INFORMATION

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Splice variant	Ensembl	UniProt	Protein class	Gene ontology	Length (aa)	Molecular mass (kDa)	Signal peptide (predicted)	Transmembrane regions (predicted)
FN1-001	ENSP00000346839 ENST00000354785	P02751 Show all » « Hide P02751 [Direct mapping] Fibronectin Anastellin Ugl-Y1 Ugl-Y2 Ugl-Y3 A6YID6 [Target identity:25%; Query identity:100%] Fibronectin splice variant E {ECO:0000313\|EMBL:ABR68538.1} Q7L553 [Target identity:8%; Query identity:100%] FN1 protein {ECO:0000313\|EMBL:AAH05858.2} Q9H382 [Target identity:6%; Query identity:100%] Fibronectin 1 {ECO:0000313\|EMBL:AAP35502.1}; PRO2841 {ECO:0000313\|EMBL:AAG35520.1} Q53S27 [Target identity:5%; Query identity:100%] Putative uncharacterized protein FN1 {ECO:0000313\|EMBL:AAY24063.1}	Show » « Hide Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Mutational cancer driver genes Candidate cardiovascular disease genes Disease related genes FDA approved drug targets Biotech drugs Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0001525 [angiogenesis] GO:0002020 [protease binding] GO:0002576 [platelet degranulation] GO:0005178 [integrin binding] GO:0005515 [protein binding] GO:0005518 [collagen binding] GO:0005576 [extracellular region] GO:0005577 [fibrinogen complex] GO:0005604 [basement membrane] GO:0005605 [basal lamina] GO:0005615 [extracellular space] GO:0005793 [endoplasmic reticulum-Golgi intermediate compartment] GO:0006953 [acute-phase response] GO:0007044 [cell-substrate junction assembly] GO:0007155 [cell adhesion] GO:0007160 [cell-matrix adhesion] GO:0007161 [calcium-independent cell-matrix adhesion] GO:0007596 [blood coagulation] GO:0008201 [heparin binding] GO:0008360 [regulation of cell shape] GO:0009611 [response to wounding] GO:0010952 [positive regulation of peptidase activity] GO:0016324 [apical plasma membrane] GO:0016504 [peptidase activator activity] GO:0018149 [peptide cross-linking] GO:0022617 [extracellular matrix disassembly] GO:0030168 [platelet activation] GO:0030198 [extracellular matrix organization] GO:0031012 [extracellular matrix] GO:0031093 [platelet alpha granule lumen] GO:0033622 [integrin activation] GO:0034446 [substrate adhesion-dependent cell spreading] GO:0035987 [endodermal cell differentiation] GO:0042060 [wound healing] GO:0045773 [positive regulation of axon extension] GO:0050900 [leukocyte migration] GO:0070062 [extracellular vesicular exosome] GO:0072562 [blood microparticle]	2477	272.3	Yes	0
FN1-002	ENSP00000323534 ENST00000323926	P02751 Show all » « Hide P02751 [Direct mapping] Fibronectin Anastellin Ugl-Y1 Ugl-Y2 Ugl-Y3 A6YID2 [Target identity:25%; Query identity:100%] Fibronectin splice variant A {ECO:0000313\|EMBL:ABR68534.1} Q7L553 [Target identity:8%; Query identity:100%] FN1 protein {ECO:0000313\|EMBL:AAH05858.2} Q9H382 [Target identity:6%; Query identity:100%] Fibronectin 1 {ECO:0000313\|EMBL:AAP35502.1}; PRO2841 {ECO:0000313\|EMBL:AAG35520.1} Q53S27 [Target identity:5%; Query identity:100%] Putative uncharacterized protein FN1 {ECO:0000313\|EMBL:AAY24063.1}	Show » « Hide Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Mutational cancer driver genes Candidate cardiovascular disease genes Disease related genes FDA approved drug targets Biotech drugs Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0001525 [angiogenesis] GO:0002020 [protease binding] GO:0002576 [platelet degranulation] GO:0005178 [integrin binding] GO:0005515 [protein binding] GO:0005518 [collagen binding] GO:0005576 [extracellular region] GO:0005577 [fibrinogen complex] GO:0005615 [extracellular space] GO:0005793 [endoplasmic reticulum-Golgi intermediate compartment] GO:0006953 [acute-phase response] GO:0007155 [cell adhesion] GO:0007596 [blood coagulation] GO:0008201 [heparin binding] GO:0008360 [regulation of cell shape] GO:0009611 [response to wounding] GO:0018149 [peptide cross-linking] GO:0022617 [extracellular matrix disassembly] GO:0030168 [platelet activation] GO:0030198 [extracellular matrix organization] GO:0031012 [extracellular matrix] GO:0031093 [platelet alpha granule lumen] GO:0033622 [integrin activation] GO:0034446 [substrate adhesion-dependent cell spreading] GO:0035987 [endodermal cell differentiation] GO:0050900 [leukocyte migration] GO:0070062 [extracellular vesicular exosome] GO:0072562 [blood microparticle]	2446	268.9	Yes	0
FN1-003	ENSP00000338200 ENST00000336916	P02751 Show all » « Hide P02751 [Direct mapping] Fibronectin Anastellin Ugl-Y1 Ugl-Y2 Ugl-Y3 A6YID2 [Target identity:26%; Query identity:100%] Fibronectin splice variant A {ECO:0000313\|EMBL:ABR68534.1} Q7L553 [Target identity:8%; Query identity:100%] FN1 protein {ECO:0000313\|EMBL:AAH05858.2} Q9H382 [Target identity:6%; Query identity:100%] Fibronectin 1 {ECO:0000313\|EMBL:AAP35502.1}; PRO2841 {ECO:0000313\|EMBL:AAG35520.1} Q53S27 [Target identity:5%; Query identity:100%] Putative uncharacterized protein FN1 {ECO:0000313\|EMBL:AAY24063.1}	Show » « Hide Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Mutational cancer driver genes Candidate cardiovascular disease genes Disease related genes FDA approved drug targets Biotech drugs Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0001525 [angiogenesis] GO:0002020 [protease binding] GO:0002576 [platelet degranulation] GO:0005178 [integrin binding] GO:0005515 [protein binding] GO:0005518 [collagen binding] GO:0005576 [extracellular region] GO:0005577 [fibrinogen complex] GO:0005615 [extracellular space] GO:0005793 [endoplasmic reticulum-Golgi intermediate compartment] GO:0006953 [acute-phase response] GO:0007155 [cell adhesion] GO:0007596 [blood coagulation] GO:0008201 [heparin binding] GO:0008360 [regulation of cell shape] GO:0009611 [response to wounding] GO:0018149 [peptide cross-linking] GO:0022617 [extracellular matrix disassembly] GO:0030168 [platelet activation] GO:0030198 [extracellular matrix organization] GO:0031012 [extracellular matrix] GO:0031093 [platelet alpha granule lumen] GO:0033622 [integrin activation] GO:0034446 [substrate adhesion-dependent cell spreading] GO:0035987 [endodermal cell differentiation] GO:0050900 [leukocyte migration] GO:0070062 [extracellular vesicular exosome] GO:0072562 [blood microparticle]	2355	259.2	Yes	0
FN1-004	ENSP00000350534 ENST00000357867	P02751 Show all » « Hide P02751 [Direct mapping] Fibronectin Anastellin Ugl-Y1 Ugl-Y2 Ugl-Y3 Q7L553 [Target identity:9%; Query identity:100%] FN1 protein {ECO:0000313\|EMBL:AAH05858.2} Q9H382 [Target identity:7%; Query identity:100%] Fibronectin 1 {ECO:0000313\|EMBL:AAP35502.1}; PRO2841 {ECO:0000313\|EMBL:AAG35520.1} Q53S27 [Target identity:6%; Query identity:100%] Putative uncharacterized protein FN1 {ECO:0000313\|EMBL:AAY24063.1}	Show » « Hide Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Mutational cancer driver genes Candidate cardiovascular disease genes Disease related genes FDA approved drug targets Biotech drugs Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0001525 [angiogenesis] GO:0002020 [protease binding] GO:0002576 [platelet degranulation] GO:0005178 [integrin binding] GO:0005515 [protein binding] GO:0005518 [collagen binding] GO:0005576 [extracellular region] GO:0005577 [fibrinogen complex] GO:0005615 [extracellular space] GO:0005793 [endoplasmic reticulum-Golgi intermediate compartment] GO:0006953 [acute-phase response] GO:0007155 [cell adhesion] GO:0007596 [blood coagulation] GO:0008201 [heparin binding] GO:0008360 [regulation of cell shape] GO:0009611 [response to wounding] GO:0018149 [peptide cross-linking] GO:0022617 [extracellular matrix disassembly] GO:0030168 [platelet activation] GO:0030198 [extracellular matrix organization] GO:0031012 [extracellular matrix] GO:0031093 [platelet alpha granule lumen] GO:0033622 [integrin activation] GO:0034446 [substrate adhesion-dependent cell spreading] GO:0035987 [endodermal cell differentiation] GO:0050900 [leukocyte migration] GO:0070062 [extracellular vesicular exosome] GO:0072562 [blood microparticle]	2176	239.6	Yes	0
FN1-005	ENSP00000394423 ENST00000421182	P02751 Show all » « Hide P02751 [Direct mapping] Fibronectin Anastellin Ugl-Y1 Ugl-Y2 Ugl-Y3 Q7L553 [Target identity:9%; Query identity:100%] FN1 protein {ECO:0000313\|EMBL:AAH05858.2} Q9H382 [Target identity:7%; Query identity:100%] Fibronectin 1 {ECO:0000313\|EMBL:AAP35502.1}; PRO2841 {ECO:0000313\|EMBL:AAG35520.1} Q53S27 [Target identity:6%; Query identity:100%] Putative uncharacterized protein FN1 {ECO:0000313\|EMBL:AAY24063.1} Q14328 [Target identity:1%; Query identity:100%] FN1 protein {ECO:0000313\|EMBL:AAA52466.1}	Show » « Hide Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Mutational cancer driver genes Candidate cardiovascular disease genes Disease related genes FDA approved drug targets Biotech drugs Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0001525 [angiogenesis] GO:0002020 [protease binding] GO:0002576 [platelet degranulation] GO:0005178 [integrin binding] GO:0005515 [protein binding] GO:0005518 [collagen binding] GO:0005576 [extracellular region] GO:0005577 [fibrinogen complex] GO:0005615 [extracellular space] GO:0005793 [endoplasmic reticulum-Golgi intermediate compartment] GO:0006953 [acute-phase response] GO:0007155 [cell adhesion] GO:0007596 [blood coagulation] GO:0008201 [heparin binding] GO:0008360 [regulation of cell shape] GO:0009611 [response to wounding] GO:0018149 [peptide cross-linking] GO:0022617 [extracellular matrix disassembly] GO:0030168 [platelet activation] GO:0030198 [extracellular matrix organization] GO:0031012 [extracellular matrix] GO:0031093 [platelet alpha granule lumen] GO:0033622 [integrin activation] GO:0034446 [substrate adhesion-dependent cell spreading] GO:0035987 [endodermal cell differentiation] GO:0050900 [leukocyte migration] GO:0070062 [extracellular vesicular exosome] GO:0072562 [blood microparticle]	2240	246.7	Yes	0
FN1-008	ENSP00000410422 ENST00000446046	P02751 Show all » « Hide P02751 [Direct mapping] Fibronectin Anastellin Ugl-Y1 Ugl-Y2 Ugl-Y3 A6YID3 [Target identity:25%; Query identity:100%] Fibronectin splice variant B {ECO:0000313\|EMBL:ABR68535.1} Q7L553 [Target identity:9%; Query identity:100%] FN1 protein {ECO:0000313\|EMBL:AAH05858.2} Q9H382 [Target identity:6%; Query identity:100%] Fibronectin 1 {ECO:0000313\|EMBL:AAP35502.1}; PRO2841 {ECO:0000313\|EMBL:AAG35520.1} Q53S27 [Target identity:5%; Query identity:100%] Putative uncharacterized protein FN1 {ECO:0000313\|EMBL:AAY24063.1} Q14328 [Target identity:1%; Query identity:100%] FN1 protein {ECO:0000313\|EMBL:AAA52466.1}	Show » « Hide Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Mutational cancer driver genes Candidate cardiovascular disease genes Disease related genes FDA approved drug targets Biotech drugs Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0001525 [angiogenesis] GO:0002020 [protease binding] GO:0002576 [platelet degranulation] GO:0005178 [integrin binding] GO:0005515 [protein binding] GO:0005518 [collagen binding] GO:0005576 [extracellular region] GO:0005577 [fibrinogen complex] GO:0005615 [extracellular space] GO:0005793 [endoplasmic reticulum-Golgi intermediate compartment] GO:0006953 [acute-phase response] GO:0007155 [cell adhesion] GO:0007596 [blood coagulation] GO:0008201 [heparin binding] GO:0008360 [regulation of cell shape] GO:0009611 [response to wounding] GO:0018149 [peptide cross-linking] GO:0022617 [extracellular matrix disassembly] GO:0030168 [platelet activation] GO:0030198 [extracellular matrix organization] GO:0031012 [extracellular matrix] GO:0031093 [platelet alpha granule lumen] GO:0033622 [integrin activation] GO:0034446 [substrate adhesion-dependent cell spreading] GO:0035987 [endodermal cell differentiation] GO:0050900 [leukocyte migration] GO:0070062 [extracellular vesicular exosome] GO:0072562 [blood microparticle]	2330	256.5	Yes	0
FN1-009	ENSP00000415018 ENST00000443816	P02751 Show all » « Hide P02751 [Direct mapping] Fibronectin Anastellin Ugl-Y1 Ugl-Y2 Ugl-Y3 A6YID4 [Target identity:23%; Query identity:100%] Fibronectin splice variant C {ECO:0000313\|EMBL:ABR68536.1} Q7L553 [Target identity:9%; Query identity:100%] FN1 protein {ECO:0000313\|EMBL:AAH05858.2} Q9H382 [Target identity:7%; Query identity:100%] Fibronectin 1 {ECO:0000313\|EMBL:AAP35502.1}; PRO2841 {ECO:0000313\|EMBL:AAG35520.1} Q53S27 [Target identity:6%; Query identity:100%] Putative uncharacterized protein FN1 {ECO:0000313\|EMBL:AAY24063.1}	Show » « Hide Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Mutational cancer driver genes Candidate cardiovascular disease genes Disease related genes FDA approved drug targets Biotech drugs Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0001525 [angiogenesis] GO:0002020 [protease binding] GO:0002576 [platelet degranulation] GO:0005178 [integrin binding] GO:0005515 [protein binding] GO:0005518 [collagen binding] GO:0005576 [extracellular region] GO:0005577 [fibrinogen complex] GO:0005615 [extracellular space] GO:0005793 [endoplasmic reticulum-Golgi intermediate compartment] GO:0006953 [acute-phase response] GO:0007155 [cell adhesion] GO:0007596 [blood coagulation] GO:0008201 [heparin binding] GO:0008360 [regulation of cell shape] GO:0009611 [response to wounding] GO:0018149 [peptide cross-linking] GO:0022617 [extracellular matrix disassembly] GO:0030168 [platelet activation] GO:0030198 [extracellular matrix organization] GO:0031012 [extracellular matrix] GO:0031093 [platelet alpha granule lumen] GO:0033622 [integrin activation] GO:0034446 [substrate adhesion-dependent cell spreading] GO:0035987 [endodermal cell differentiation] GO:0050900 [leukocyte migration] GO:0070062 [extracellular vesicular exosome] GO:0072562 [blood microparticle]	2265	249.4	Yes	0
FN1-011	ENSP00000416139 ENST00000456923	H0Y7Z1 Show all » « Hide H0Y7Z1 [Target identity:100%; Query identity:100%] Ugl-Y3 {ECO:0000313\|Ensembl:ENSP00000416139} Q7L553 [Target identity:19%; Query identity:100%] FN1 protein {ECO:0000313\|EMBL:AAH05858.2} Q9H382 [Target identity:14%; Query identity:100%] Fibronectin 1 {ECO:0000313\|EMBL:AAP35502.1}; PRO2841 {ECO:0000313\|EMBL:AAG35520.1} Q53S27 [Target identity:12%; Query identity:100%] Putative uncharacterized protein FN1 {ECO:0000313\|EMBL:AAY24063.1}	Show » « Hide Predicted intracellular proteins Cancer-related genes Mutational cancer driver genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0005515 [protein binding] GO:0005576 [extracellular region]	1103	120.8	No	0
FN1-012	ENSP00000399538 ENST00000432072	P02751 Show all » « Hide P02751 [Direct mapping] Fibronectin Anastellin Ugl-Y1 Ugl-Y2 Ugl-Y3 Q7L553 [Target identity:9%; Query identity:100%] FN1 protein {ECO:0000313\|EMBL:AAH05858.2} Q9H382 [Target identity:7%; Query identity:100%] Fibronectin 1 {ECO:0000313\|EMBL:AAP35502.1}; PRO2841 {ECO:0000313\|EMBL:AAG35520.1} Q53S27 [Target identity:6%; Query identity:100%] Putative uncharacterized protein FN1 {ECO:0000313\|EMBL:AAY24063.1}	Show » « Hide Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Mutational cancer driver genes Candidate cardiovascular disease genes Disease related genes FDA approved drug targets Biotech drugs Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0001525 [angiogenesis] GO:0002020 [protease binding] GO:0002576 [platelet degranulation] GO:0005178 [integrin binding] GO:0005515 [protein binding] GO:0005518 [collagen binding] GO:0005576 [extracellular region] GO:0005577 [fibrinogen complex] GO:0005615 [extracellular space] GO:0005793 [endoplasmic reticulum-Golgi intermediate compartment] GO:0006953 [acute-phase response] GO:0007155 [cell adhesion] GO:0007596 [blood coagulation] GO:0008201 [heparin binding] GO:0008360 [regulation of cell shape] GO:0009611 [response to wounding] GO:0018149 [peptide cross-linking] GO:0022617 [extracellular matrix disassembly] GO:0030168 [platelet activation] GO:0030198 [extracellular matrix organization] GO:0031012 [extracellular matrix] GO:0031093 [platelet alpha granule lumen] GO:0033622 [integrin activation] GO:0034446 [substrate adhesion-dependent cell spreading] GO:0035987 [endodermal cell differentiation] GO:0050900 [leukocyte migration] GO:0070062 [extracellular vesicular exosome] GO:0072562 [blood microparticle]	2267	249.3	Yes	0
FN1-013	ENSP00000348285 ENST00000356005	P02751 Show all » « Hide P02751 [Direct mapping] Fibronectin Anastellin Ugl-Y1 Ugl-Y2 Ugl-Y3 Q7L553 [Target identity:9%; Query identity:100%] FN1 protein {ECO:0000313\|EMBL:AAH05858.2} Q9H382 [Target identity:7%; Query identity:100%] Fibronectin 1 {ECO:0000313\|EMBL:AAP35502.1}; PRO2841 {ECO:0000313\|EMBL:AAG35520.1} Q53S27 [Target identity:5%; Query identity:100%] Putative uncharacterized protein FN1 {ECO:0000313\|EMBL:AAY24063.1}	Show » « Hide Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Mutational cancer driver genes Candidate cardiovascular disease genes Disease related genes FDA approved drug targets Biotech drugs Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0001525 [angiogenesis] GO:0002020 [protease binding] GO:0002576 [platelet degranulation] GO:0005178 [integrin binding] GO:0005515 [protein binding] GO:0005518 [collagen binding] GO:0005576 [extracellular region] GO:0005577 [fibrinogen complex] GO:0005615 [extracellular space] GO:0005793 [endoplasmic reticulum-Golgi intermediate compartment] GO:0006953 [acute-phase response] GO:0007155 [cell adhesion] GO:0007596 [blood coagulation] GO:0008201 [heparin binding] GO:0008360 [regulation of cell shape] GO:0009611 [response to wounding] GO:0018149 [peptide cross-linking] GO:0022617 [extracellular matrix disassembly] GO:0030168 [platelet activation] GO:0030198 [extracellular matrix organization] GO:0031012 [extracellular matrix] GO:0031093 [platelet alpha granule lumen] GO:0033622 [integrin activation] GO:0034446 [substrate adhesion-dependent cell spreading] GO:0035987 [endodermal cell differentiation] GO:0050900 [leukocyte migration] GO:0070062 [extracellular vesicular exosome] GO:0072562 [blood microparticle]	2296	252.8	Yes	0
FN1-014	ENSP00000398907 ENST00000426059	P02751 Show all » « Hide P02751 [Direct mapping] Fibronectin Anastellin Ugl-Y1 Ugl-Y2 Ugl-Y3	Show » « Hide Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Mutational cancer driver genes Candidate cardiovascular disease genes Disease related genes FDA approved drug targets Biotech drugs Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0001525 [angiogenesis] GO:0002020 [protease binding] GO:0002576 [platelet degranulation] GO:0005178 [integrin binding] GO:0005515 [protein binding] GO:0005518 [collagen binding] GO:0005576 [extracellular region] GO:0005577 [fibrinogen complex] GO:0005615 [extracellular space] GO:0005793 [endoplasmic reticulum-Golgi intermediate compartment] GO:0006953 [acute-phase response] GO:0007155 [cell adhesion] GO:0007596 [blood coagulation] GO:0008201 [heparin binding] GO:0008360 [regulation of cell shape] GO:0009611 [response to wounding] GO:0018149 [peptide cross-linking] GO:0022617 [extracellular matrix disassembly] GO:0030168 [platelet activation] GO:0030198 [extracellular matrix organization] GO:0031012 [extracellular matrix] GO:0031093 [platelet alpha granule lumen] GO:0033622 [integrin activation] GO:0034446 [substrate adhesion-dependent cell spreading] GO:0035987 [endodermal cell differentiation] GO:0050900 [leukocyte migration] GO:0070062 [extracellular vesicular exosome] GO:0072562 [blood microparticle]	657	73.7	Yes	0
FN1-026	ENSP00000392565 ENST00000438981	H0Y4K8 Show all » « Hide H0Y4K8 [Target identity:100%; Query identity:100%] Ugl-Y3 {ECO:0000313\|Ensembl:ENSP00000392565} Q14328 [Target identity:16%; Query identity:100%] FN1 protein {ECO:0000313\|EMBL:AAA52466.1}	Show » « Hide Predicted intracellular proteins Cancer-related genes Mutational cancer driver genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0005515 [protein binding]	241	26.6	No	0
FN1-201	ENSP00000352696 ENST00000359671	P02751 Show all » « Hide P02751 [Direct mapping] Fibronectin Anastellin Ugl-Y1 Ugl-Y2 Ugl-Y3 A6YID6 [Target identity:26%; Query identity:100%] Fibronectin splice variant E {ECO:0000313\|EMBL:ABR68538.1} Q7L553 [Target identity:8%; Query identity:100%] FN1 protein {ECO:0000313\|EMBL:AAH05858.2} Q9H382 [Target identity:6%; Query identity:100%] Fibronectin 1 {ECO:0000313\|EMBL:AAP35502.1}; PRO2841 {ECO:0000313\|EMBL:AAG35520.1} Q53S27 [Target identity:5%; Query identity:100%] Putative uncharacterized protein FN1 {ECO:0000313\|EMBL:AAY24063.1}	Show » « Hide Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Cancer-related genes Candidate cancer biomarkers Mutational cancer driver genes Candidate cardiovascular disease genes Disease related genes FDA approved drug targets Biotech drugs Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0001525 [angiogenesis] GO:0002020 [protease binding] GO:0002576 [platelet degranulation] GO:0005178 [integrin binding] GO:0005515 [protein binding] GO:0005518 [collagen binding] GO:0005576 [extracellular region] GO:0005577 [fibrinogen complex] GO:0005615 [extracellular space] GO:0005793 [endoplasmic reticulum-Golgi intermediate compartment] GO:0006953 [acute-phase response] GO:0007155 [cell adhesion] GO:0007596 [blood coagulation] GO:0008201 [heparin binding] GO:0008360 [regulation of cell shape] GO:0009611 [response to wounding] GO:0018149 [peptide cross-linking] GO:0022617 [extracellular matrix disassembly] GO:0030168 [platelet activation] GO:0030198 [extracellular matrix organization] GO:0031012 [extracellular matrix] GO:0031093 [platelet alpha granule lumen] GO:0033622 [integrin activation] GO:0034446 [substrate adhesion-dependent cell spreading] GO:0035987 [endodermal cell differentiation] GO:0050900 [leukocyte migration] GO:0070062 [extracellular vesicular exosome] GO:0072562 [blood microparticle]	2386	262.6	Yes	0

The Human Protein Atlas project is funded by the Knut & Alice Wallenberg foundation.