ODC1

GENE INFORMATION

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Gene name

ODC1 (HGNC Symbol)

Synonyms

ODC

Description

Ornithine decarboxylase 1 (HGNC Symbol)

Entrez gene summary

This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Dec 2013]

Chromosome

2

Cytoband

p25.1

Chromosome location (bp)

10439968 - 10448504

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000115758 (version 78.38)

Entrez gene

4953

UniProt

P11926 (UniProt - Evidence at protein level)

neXtProt

NX_P11926

Antibodypedia

ODC1 antibodies
 

PROTEIN VIEW

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ODC1-001
 
ODC1-002
 
ODC1-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ODC1-001 ENSP00000234111
ENST00000234111
P11926
Show all »
Show » Show » 461 51.1 No 0
ODC1-002 ENSP00000385333
ENST00000405333
P11926
Show all »
Show » Show » 461 51.1 No 0
ODC1-003 ENSP00000390691
ENST00000443218
C9JG30
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Show » Show » 68 7.9 No 0