KYNU

GENE INFORMATION

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Gene name

KYNU

Synonyms

Description

Kynureninase (HGNC Symbol)

Entrez gene summary

Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010]

Chromosome

2

Cytoband

q22.2

Chromosome location (bp)

142877498 - 143055832

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000115919 (version 78.38)

Entrez gene

8942

UniProt

Q16719 (UniProt - Evidence at protein level)

neXtProt

NX_Q16719

Antibodypedia

KYNU antibodies
 

PROTEIN VIEW

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KYNU-001
 
KYNU-002
 
KYNU-003
 
KYNU-004
 
KYNU-007
 
KYNU-008
 
KYNU-009
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KYNU-001 ENSP00000264170
ENST00000264170
Q16719
Show all »
Show » Show » 465 52.4 No 0
KYNU-002 ENSP00000386731
ENST00000409512
Q16719
Show all »
Show » Show » 465 52.4 No 0
KYNU-003 ENSP00000364928
ENST00000375773
Q16719
Show all »
Show » Show » 307 34.6 No 0
KYNU-004 ENSP00000387296
ENST00000410015
B8ZZA3
Show all »
Show » Show » 148 16.7 No 0
KYNU-007 ENSP00000484801
ENST00000621320
Show » Show » 236 26.8 No 0
KYNU-008 ENSP00000481930
ENST00000612147
Show » 168 18.9 No 0
KYNU-009 ENSP00000482009
ENST00000613664
Show » 157 17.3 No 0