ICMT

GENE INFORMATION

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Gene name

ICMT (HGNC Symbol)

Synonyms

HSTE14, PCCMT, PPMT

Description

Isoprenylcysteine carboxyl methyltransferase (HGNC Symbol)

Entrez gene summary

This gene encodes the third of three enzymes that posttranslationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. This enzyme localizes to the endoplasmic reticulum. Alternative splicing may result in other transcript variants, but the biological validity of those transcripts has not been determined. [provided by RefSeq, Jul 2008]

Chromosome

1

Cytoband

p36.31

Chromosome location (bp)

6221193 - 6235972

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000116237 (version 78.38)

Entrez gene

23463

UniProt

O60725 (UniProt - Evidence at protein level)

neXtProt

NX_O60725

Antibodypedia

ICMT antibodies
 

PROTEIN VIEW

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ICMT-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ICMT-001 ENSP00000343552
ENST00000343813
O60725
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