PRDM2

GENE INFORMATION

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Gene name

PRDM2 (HGNC Symbol)

Synonyms

HUMHOXY1, KMT8, MTB-ZF, RIZ, RIZ1, RIZ2

Description

PR domain containing 2, with ZNF domain (HGNC Symbol)

Entrez gene summary

This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]

Chromosome

1

Cytoband

p36.21

Chromosome location (bp)

13700198 - 13825079

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000116731 (version 78.38)

Entrez gene

7799

UniProt

Q13029 (UniProt - Evidence at protein level)

neXtProt

NX_Q13029

Antibodypedia

PRDM2 antibodies
 

PROTEIN VIEW

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PRDM2-001
 
PRDM2-002
 
PRDM2-003
 
PRDM2-004
 
PRDM2-009
 
PRDM2-010
 
PRDM2-011
 
PRDM2-014
 
PRDM2-015
 
PRDM2-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PRDM2-001 ENSP00000235372
ENST00000235372
Q13029
Show all »
Show » Show » 1718 188.9 No 0
PRDM2-002 ENSP00000365216
ENST00000376048
Q13029
Show all »
Show » Show » 226 25.5 No 0
PRDM2-003 ENSP00000411103
ENST00000413440
Q13029
Show all »
Show » Show » 1481 162.1 No 0
PRDM2-004 ENSP00000341621
ENST00000343137
Q13029
Show all »
Show » Show » 1481 162.1 No 0
PRDM2-009 ENSP00000474273
ENST00000487453
S4R3F7
Show all »
Show » 21 2.3 No 0
PRDM2-010 ENSP00000423010
ENST00000484063
D6RAA0
Show all »
Show » Show » 153 17.3 No 0
PRDM2-011 ENSP00000425028
ENST00000503842
D6RED5
Show all »
Show » 62 6.8 No 0
PRDM2-014 ENSP00000384430
ENST00000407521
D6RJM6
Show all »
Show » 78 8.6 No 0
PRDM2-015 ENSP00000426737
ENST00000505823
D6RED5
Show all »
Show » 62 6.8 No 0
PRDM2-201 ENSP00000312352
ENST00000311066
Q13029
Show all »
Show » Show » 1682 185 No 0