BMP8B

GENE INFORMATION

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Gene name

BMP8B (HGNC Symbol)

Synonyms

BMP8, OP-2

Description

Bone morphogenetic protein 8b (HGNC Symbol)

Entrez gene summary

The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has led to speculation of possible bone inductive activity. [provided by RefSeq, Jul 2008]

Chromosome

1

Cytoband

p34.2

Chromosome location (bp)

39757182 - 39788861

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000116985 (version 78.38)

Entrez gene

656

UniProt

P34820 (UniProt - Evidence at transcript level)

neXtProt

NX_P34820

Antibodypedia

BMP8B antibodies
 

PROTEIN VIEW

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BMP8B-001
 
BMP8B-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

BMP8B-001 ENSP00000361915
ENST00000372827
P34820
Show all »
Show » Show » 402 44.8 Yes 0
BMP8B-201 ENSP00000380518
ENST00000397360
E7EMY8
Show all »
Show » Show » 349 39.2 Yes 0