CD48

GENE INFORMATION

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Gene name

CD48 (HGNC Symbol)

Synonyms

BCM1, BLAST, hCD48, mCD48, SLAMF2

Description

CD48 molecule (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the CD2 subfamily of immunoglobulin-like receptors which includes SLAM (signaling lymphocyte activation molecules) proteins. The encoded protein is found on the surface of lymphocytes and other immune cells, dendritic cells and endothelial cells, and participates in activation and differentiation pathways in these cells. The encoded protein does not have a transmembrane domain, however, but is held at the cell surface by a GPI anchor via a C-terminal domain which maybe cleaved to yield a soluble form of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

Chromosome

1

Cytoband

q23.3

Chromosome location (bp)

160678746 - 160711851

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000117091 (version 78.38)

Entrez gene

962

UniProt

P09326 (UniProt - Evidence at protein level)

neXtProt

NX_P09326

Antibodypedia

CD48 antibodies
 

PROTEIN VIEW

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CD48-001
 
CD48-002
 
CD48-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CD48-001 ENSP00000357025
ENST00000368046
P09326
Show all »
Show » Show » 243 27.7 Yes 1
CD48-002 ENSP00000357024
ENST00000368045
P09326
Show all »
Show » Show » 169 19.4 Yes 0
CD48-003 ENSP00000484431
ENST00000613788
Show » Show » 252 28.9 Yes 0