ARG1

GENE INFORMATION

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Gene name

ARG1

Synonyms

Description

Arginase 1 (HGNC Symbol)

Entrez gene summary

Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

Chromosome

6

Cytoband

q23.2

Chromosome location (bp)

131573144 - 131584332

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000118520 (version 78.38)

Entrez gene

383

UniProt

P05089 (UniProt - Evidence at protein level)

neXtProt

NX_P05089

Antibodypedia

ARG1 antibodies
 

PROTEIN VIEW

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ARG1-001
 
ARG1-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ARG1-001 ENSP00000357066
ENST00000368087
P05089
Show all »
Show » Show » 322 34.7 No 0
ARG1-004 ENSP00000349446
ENST00000356962
P05089
Show all »
Show » Show » 330 35.7 No 0