FOXO3

GENE INFORMATION

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Gene name

FOXO3 (HGNC Symbol)

Synonyms

AF6q21, FKHRL1, FOXO2, FOXO3A

Description

Forkhead box O3 (HGNC Symbol)

Entrez gene summary

This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]

Chromosome

6

Cytoband

q21

Chromosome location (bp)

108559835 - 108684774

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000118689 (version 78.38)

Entrez gene

2309

UniProt

O43524 (UniProt - Evidence at protein level)

neXtProt

NX_O43524

Antibodypedia

FOXO3 antibodies
 

PROTEIN VIEW

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FOXO3-001
 
FOXO3-201
 
FOXO3-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FOXO3-001 ENSP00000339527
ENST00000343882
O43524
Show all »
Show » Show » 673 71.3 No 0
FOXO3-201 ENSP00000385824
ENST00000406360
O43524
Show all »
Show » Show » 673 71.3 No 0
FOXO3-202 ENSP00000446316
ENST00000540898
O43524
Show all »
Show » Show » 453 48.4 No 0