RHOQ

GENE INFORMATION

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Gene name

RHOQ (HGNC Symbol)

Synonyms

ARHQ, RASL7A, TC10

Description

Ras homolog family member Q (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The encoded protein is an important signalling protein for sarcomere assembly and has been shown to play a significant role in the exocytosis of the solute carrier family 2, facilitated glucose transporter member 4 and other proteins, possibly acting as the signal that turns on the membrane fusion machinery. Three related pseudogene have been identified on chromosomes 2 and 14. [provided by RefSeq, Aug 2011]

Chromosome

2

Cytoband

p21

Chromosome location (bp)

46541806 - 46583121

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000119729 (version 78.38)

Entrez gene

23433

UniProt

P17081 (UniProt - Evidence at protein level)

neXtProt

NX_P17081

Antibodypedia

RHOQ antibodies
 

PROTEIN VIEW

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RHOQ-001
 
RHOQ-002
 
RHOQ-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

RHOQ-001 ENSP00000238738
ENST00000238738
P17081
Show all »
Show » Show » 205 22.7 No 0
RHOQ-002 ENSP00000428006
ENST00000482449
E5RFZ3
Show all »
Show » Show » 75 8.6 Yes 0
RHOQ-201 ENSP00000484856
ENST00000616091
P17081
Show all »
Show » Show » 213 23.4 No 0