HOXB5

GENE INFORMATION

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Gene name

HOXB5 (HGNC Symbol)

Synonyms

HOX2, HOX2A

Description

Homeobox B5 (HGNC Symbol)

Entrez gene summary

This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in lung and gut development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML) and the occurrence of bronchopulmonary sequestration (BPS) and congenital cystic adenomatoid malformation (CCAM) tissue. [provided by RefSeq, Jul 2008]

Chromosome

17

Cytoband

q21.32

Chromosome location (bp)

48591257 - 48593961

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000120075 (version 78.38)

Entrez gene

3215

UniProt

P09067 (UniProt - Evidence at transcript level)

neXtProt

NX_P09067

Antibodypedia

HOXB5 antibodies
 

PROTEIN VIEW

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HOXB5-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HOXB5-001 ENSP00000239151
ENST00000239151
P09067
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