TBX4

GENE INFORMATION

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Gene name

TBX4

Synonyms

Description

T-box 4 (HGNC Symbol)

Entrez gene summary

This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human homolog of mouse Tbx4, which is closely linked to Tbx2 on mouse chromosome 11. Similarly this gene, like TBX2, maps to human chromosome 17. Expression studies in mouse and chicken show that Tbx4 is expressed in developing hindlimb, but not in forelimb buds, suggesting a role for this gene in regulating limb development and specification of limb identity. [provided by RefSeq, Jul 2008]

Chromosome

17

Cytoband

q23.2

Chromosome location (bp)

61452404 - 61485110

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000121075 (version 78.38)

Entrez gene

9496

UniProt

P57082 (UniProt - Evidence at protein level)

neXtProt

NX_P57082

Antibodypedia

TBX4 antibodies
 

PROTEIN VIEW

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TBX4-001
 
TBX4-002
 
TBX4-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TBX4-001 ENSP00000377435
ENST00000393853
P57082
Show all »
Show » Show » 546 60.3 No 0
TBX4-002 ENSP00000240335
ENST00000240335
P57082
Show all »
Show » Show » 545 60.2 No 0
TBX4-003 ENSP00000467588
ENST00000589003
K7EPY2
Show all »
Show » Show » 135 15.5 No 0