GHSR

GENE INFORMATION

? »

Gene name

GHSR

Synonyms

Description

Growth hormone secretagogue receptor (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the G-protein coupled receptor family. The encoded protein may play a role in energy homeostasis and regulation of body weight. Two identified transcript variants are expressed in several tissues and are evolutionary conserved in fish and swine. One transcript, 1a, excises an intron and encodes the functional protein; this protein is the receptor for the Ghrelin ligand and defines a neuroendocrine pathway for growth hormone release. The second transcript (1b) retains the intron and does not function as a receptor for Ghrelin; however, it may function to attenuate activity of isoform 1a. Mutations in this gene are associated with autosomal idiopathic short stature.[provided by RefSeq, Apr 2010]

Chromosome

3

Cytoband

q26.31

Chromosome location (bp)

172445133 - 172448456

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000121853 (version 78.38)

Entrez gene

2693

UniProt

Q92847 (UniProt - Evidence at protein level)

neXtProt

NX_Q92847

Antibodypedia

GHSR antibodies
 

PROTEIN VIEW

? »
 
 
 
GHSR-001
 
GHSR-002
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GHSR-001 ENSP00000241256
ENST00000241256
Q92847
Show all »
Show » Show » 366 41.3 No 7
GHSR-002 ENSP00000395344
ENST00000427970
Q92847
Show all »
Show » Show » 289 32.2 No 6