GTF3A

GENE INFORMATION

? »

Gene name

GTF3A (HGNC Symbol)

Synonyms

AP2, TFIIIA

Description

General transcription factor IIIA (HGNC Symbol)

Entrez gene summary

The product of this gene is a zinc finger protein with nine Cis[2]-His[2] zinc finger domains. It functions as an RNA polymerase III transcription factor to induce transcription of the 5S rRNA genes. The protein binds to a 50 bp internal promoter in the 5S genes called the internal control region (ICR), and nucleates formation of a stable preinitiation complex. This complex recruits the TFIIIC and TFIIIB transcription factors and RNA polymerase III to form the complete transcription complex. The protein is thought to be translated using a non-AUG translation initiation site in mammals based on sequence analysis, protein homology, and the size of the purified protein. [provided by RefSeq, Jul 2008]

Chromosome

13

Cytoband

q12.2

Chromosome location (bp)

27424544 - 27435823

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000122034 (version 78.38)

Entrez gene

2971

UniProt

Q92664 (UniProt - Evidence at protein level)

neXtProt

NX_Q92664

Antibodypedia

GTF3A antibodies
 

PROTEIN VIEW

? »
 
 
 
GTF3A-001
 
GTF3A-201
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GTF3A-001 ENSP00000370532
ENST00000381140
Q92664
Show all »
Show » Show » 365 41.5 No 0
GTF3A-201 ENSP00000393050
ENST00000439403
Show » Show » 422 46.9 No 0