CD244

GENE INFORMATION

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Gene name

CD244 (HGNC Symbol)

Synonyms

2B4, NAIL, NKR2B4, Nmrk, SLAMF4

Description

CD244 molecule, natural killer cell receptor 2B4 (HGNC Symbol)

Entrez gene summary

This gene encodes a cell surface receptor expressed on natural killer (NK) cells (and some T cells) that mediate non-major histocompatibility complex (MHC) restricted killing. The interaction between NK-cell and target cells via this receptor is thought to modulate NK-cell cytolytic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009]

Chromosome

1

Cytoband

q23.3

Chromosome location (bp)

160830160 - 160862855

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000122223 (version 78.38)

Entrez gene

51744

UniProt

Q9BZW8 (UniProt - Evidence at protein level)

neXtProt

NX_Q9BZW8

Antibodypedia

CD244 antibodies
 

PROTEIN VIEW

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CD244-001
 
CD244-002
 
CD244-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CD244-001 ENSP00000357013
ENST00000368034
Q9BZW8
Show all »
Show » Show » 365 41.1 Yes 1
CD244-002 ENSP00000357012
ENST00000368033
Q9BZW8
Show all »
Show » Show » 370 41.6 Yes 1
CD244-004 ENSP00000313619
ENST00000322302
Q9BZW8
Show all »
Show » Show » 273 30.8 Yes 1