SFTPA1

GENE INFORMATION

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Gene name

SFTPA1 (HGNC Symbol)

Synonyms

COLEC4, SFTP1, SP-A, SP-A1

Description

Surfactant protein A1 (HGNC Symbol)

Entrez gene summary

This gene encodes a lung surfactant protein that is a member of a subfamily of C-type lectins called collectins. The encoded protein binds specific carbohydrate moieties found on lipids and on the surface of microorganisms. This protein plays an essential role in surfactant homeostasis and in the defense against respiratory pathogens. Mutations in this gene are associated with idiopathic pulmonary fibrosis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]

Chromosome

10

Cytoband

q22.3

Chromosome location (bp)

79610939 - 79615455

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000122852 (version 78.38)

Entrez gene

653509

UniProt

Q8IWL2 (UniProt - Evidence at protein level)

neXtProt

NX_Q8IWL2

Antibodypedia

SFTPA1 antibodies
 

PROTEIN VIEW

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SFTPA1-007
 
SFTPA1-008
 
SFTPA1-009
 
SFTPA1-201
 
SFTPA1-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SFTPA1-007 ENSP00000395527
ENST00000429958
Q8IWL2
Show all »
Show » Show » 158 16 Yes 0
SFTPA1-008 ENSP00000397082
ENST00000419470
Q8IWL2
Show all »
Show » Show » 263 27.7 Yes 0
SFTPA1-009 ENSP00000401649
ENST00000439264
Q8IWL2
Show all »
Show » Show » 158 16 Yes 0
SFTPA1-201 ENSP00000381633
ENST00000398636
Q8IWL2
Show all »
Show » Show » 248 26.2 Yes 0
SFTPA1-202 ENSP00000411102
ENST00000428376
Q8IWL2
Show all »
Show » Show » 248 26.2 Yes 0