DDX54

GENE INFORMATION

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Gene name

DDX54 (HGNC Symbol)

Synonyms

APR-5, DP97, MGC2835

Description

DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The nucleolar protein encoded by this gene interacts in a hormone-dependent manner with nuclear receptors, and represses their transcriptional activity. Alternative splice variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

12

Cytoband

q24.13

Chromosome location (bp)

113157174 - 113185479

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000123064 (version 78.38)

Entrez gene

79039

UniProt

Q8TDD1 (UniProt - Evidence at protein level)

neXtProt

NX_Q8TDD1

Antibodypedia

DDX54 antibodies
 

PROTEIN VIEW

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DDX54-001
 
DDX54-002
 
DDX54-010
 
DDX54-011
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DDX54-001 ENSP00000323858
ENST00000314045
Q8TDD1
Show all »
Show » Show » 882 98.7 No 0
DDX54-002 ENSP00000304072
ENST00000306014
Q8TDD1
Show all »
Show » Show » 881 98.6 No 0
DDX54-010 ENSP00000448477
ENST00000552375
F8VRX4
Show all »
Show » Show » 208 22.9 No 0
DDX54-011 ENSP00000447098
ENST00000546898
Show » Show » 160 18.4 No 0