MMP19

GENE INFORMATION

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Gene name

MMP19 (HGNC Symbol)

Synonyms

MMP18, RASI-1

Description

Matrix metallopeptidase 19 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of a family of proteins that are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded protein is secreted as an inactive proprotein, which is activated upon cleavage by extracellular proteases. Alternative splicing results in multiple transcript variants for this gene. [provided by RefSeq, Jan 2013]

Chromosome

12

Cytoband

q13.2

Chromosome location (bp)

55835433 - 55842966

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000123342 (version 78.38)

Entrez gene

4327

UniProt

Q99542 (UniProt - Evidence at protein level)

neXtProt

NX_Q99542

Antibodypedia

MMP19 antibodies
 

PROTEIN VIEW

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MMP19-001
 
MMP19-005
 
MMP19-011
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MMP19-001 ENSP00000313437
ENST00000322569
Q99542
Show all »
Show » Show » 508 57.4 Yes 0
MMP19-005 ENSP00000386625
ENST00000409200
Q99542
Show all »
Show » Show » 305 33.8 Yes 0
MMP19-011 ENSP00000446979
ENST00000548629
F8W1C3
Show all »
Show » Show » 485 54.6 Yes 0