TTC21B

GENE INFORMATION

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Gene name

TTC21B (HGNC Symbol)

Synonyms

FLJ11457, IFT139, JBTS11, NPHP12, THM1

Description

Tetratricopeptide repeat domain 21B (HGNC Symbol)

Entrez gene summary

This gene encodes a member of TTC21 family, containing several tetratricopeptide repeat (TPR) domains. This protein is localized to the cilium axoneme, and may play a role in retrograde intraflagellar transport in cilia. Mutations in this gene are associated with various ciliopathies, nephronophthisis 12, and asphyxiating thoracic dystrophy 4. [provided by RefSeq, Oct 2011]

Chromosome

2

Cytoband

q24.3

Chromosome location (bp)

165857475 - 165953843

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000123607 (version 78.38)

Entrez gene

79809

UniProt

Q7Z4L5 (UniProt - Evidence at protein level)

neXtProt

NX_Q7Z4L5

Antibodypedia

TTC21B antibodies
 

PROTEIN VIEW

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TTC21B-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TTC21B-001 ENSP00000243344
ENST00000243344
Q7Z4L5
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