ATP5E

GENE INFORMATION

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Gene name

ATP5E

Synonyms

Description

ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit (HGNC Symbol)

Entrez gene summary

This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the epsilon subunit of the catalytic core. Two pseudogenes of this gene are located on chromosomes 4 and 13. Read-through transcripts that include exons from this gene are expressed from the upstream gene SLMO2.[provided by RefSeq, Mar 2011]

Chromosome

20

Cytoband

q13.32

Chromosome location (bp)

59025467 - 59032382

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000124172 (version 78.38)

Entrez gene

514

UniProt

P56381 (UniProt - Evidence at protein level)

neXtProt

NX_P56381

Antibodypedia

ATP5E antibodies
 

PROTEIN VIEW

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ATP5E-001
 
ATP5E-002
 
ATP5E-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ATP5E-001 ENSP00000243997
ENST00000243997
P56381
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Show » Show » 51 5.8 No 0
ATP5E-002 ENSP00000379019
ENST00000395659
P56381
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Show » Show » 51 5.8 No 0
ATP5E-003 ENSP00000379023
ENST00000395663
P56381
Show all »
Show » Show » 51 5.8 No 0