TREM1

GENE INFORMATION

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Gene name

TREM1 (HGNC Symbol)

Synonyms

CD354, TREM-1

Description

Triggering receptor expressed on myeloid cells 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jun 2011]

Chromosome

6

Cytoband

p21.1

Chromosome location (bp)

41267926 - 41286719

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000124731 (version 78.38)

Entrez gene

54210

UniProt

Q9NP99 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NP99

Antibodypedia

TREM1 antibodies
 

PROTEIN VIEW

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TREM1-001
 
TREM1-002
 
TREM1-003
 
TREM1-007
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TREM1-001 ENSP00000244709
ENST00000244709
Q9NP99
Show all »
Show » Show » 234 26.4 Yes 1
TREM1-002 ENSP00000334284
ENST00000334475
Q9NP99
Show all »
Show » Show » 150 17.6 Yes 0
TREM1-003 ENSP00000465345
ENST00000591620
Q9NP99
Show all »
Show » Show » 225 25.6 Yes 0
TREM1-007 ENSP00000465688
ENST00000589614
K7EKM5
Show all »
Show » 250 28.4 Yes 0