DEFB126

GENE INFORMATION

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Gene name

DEFB126 (HGNC Symbol)

Synonyms

bA530N10.1, C20orf8, DEFB-26

Description

Defensin, beta 126 (HGNC Symbol)

Entrez gene summary

Defensins are cysteine-rich cationic polypeptides that are important in the immunologic response to invading microorganisms. The antimicrobial protein encoded by this gene is secreted and is a member of the beta defensin protein family. Beta defensin genes are found in several clusters throughout the genome, with this gene mapping to a cluster at 20p13. The encoded protein is highly similar to an epididymal-specific secretory protein (ESP13.2) from cynomolgus monkey. Mutation of this gene is associated with impaired sperm function. [provided by RefSeq, Nov 2014]

Chromosome

20

Cytoband

p13

Chromosome location (bp)

142369 - 145751

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000125788 (version 78.38)

Entrez gene

81623

UniProt

Q9BYW3 (UniProt - Evidence at transcript level)

neXtProt

NX_Q9BYW3

Antibodypedia

DEFB126 antibodies
 

PROTEIN VIEW

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DEFB126-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DEFB126-001 ENSP00000371835
ENST00000382398
Q9BYW3
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