FOXA2

GENE INFORMATION

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Gene name

FOXA2 (HGNC Symbol)

Synonyms

HNF3B

Description

Forkhead box A2 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific genes such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Oct 2008]

Chromosome

20

Cytoband

p11.21

Chromosome location (bp)

22581005 - 22585455

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000125798 (version 78.38)

Entrez gene

3170

UniProt

Q9Y261 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y261

Antibodypedia

FOXA2 antibodies
 

PROTEIN VIEW

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FOXA2-001
 
FOXA2-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FOXA2-001 ENSP00000366319
ENST00000377115
Q9Y261
Show all »
Show » Show » 457 48.3 No 0
FOXA2-002 ENSP00000400341
ENST00000419308
Q9Y261
Show all »
Show » Show » 463 48.9 No 0