PAX1

GENE INFORMATION

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Gene name

PAX1

Synonyms

Description

Paired box 1 (HGNC Symbol)

Entrez gene summary

This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. This gene plays a role in pattern formation during embryogenesis and may be essential for development of the vertebral column. This gene is silenced by methylation in ovarian and cervical cancers and may be a tumor suppressor gene. Mutations in this gene are also associated with vertebral malformations. [provided by RefSeq, Mar 2012]

Chromosome

20

Cytoband

p11.22

Chromosome location (bp)

21705659 - 21718486

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000125813 (version 78.38)

Entrez gene

5075

UniProt

P15863 (UniProt - Evidence at protein level)

neXtProt

NX_P15863

Antibodypedia

PAX1 antibodies
 

PROTEIN VIEW

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PAX1-001
 
PAX1-002
 
PAX1-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PAX1-001 ENSP00000381499
ENST00000398485
P15863
Show all »
Show » Show » 534 55.5 No 0
PAX1-002 ENSP00000410355
ENST00000444366
P15863
Show all »
Show » Show » 433 45.1 No 0
PAX1-201 ENSP00000481334
ENST00000613128
Show » Show » 457 47.2 No 0