CST11

GENE INFORMATION

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Gene name

CST11 (HGNC Symbol)

Synonyms

CST8L, CTES2, dJ322G13.6

Description

Cystatin 11 (HGNC Symbol)

Entrez gene summary

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes an epididymal-specific protein shown to have antimicrobial activity against E. coli. Alternative splicing yields two variants encoding distinct isoforms. [provided by RefSeq, Sep 2014]

Chromosome

20

Cytoband

p11.21

Chromosome location (bp)

23450403 - 23452857

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000125831 (version 78.38)

Entrez gene

140880

UniProt

Q9H112 (UniProt - Evidence at protein level)

neXtProt

NX_Q9H112

Antibodypedia

CST11 antibodies
 

PROTEIN VIEW

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CST11-001
 
CST11-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CST11-001 ENSP00000366208
ENST00000377009
Q9H112
Show all »
Show » Show » 138 16.5 Yes 0
CST11-002 ENSP00000366206
ENST00000377007
Q9H112
Show all »
Show » Show » 103 12.3 Yes 0