RRBP1

GENE INFORMATION

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Gene name

RRBP1 (HGNC Symbol)

Synonyms

ES/130, hES

Description

Ribosome binding protein 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a ribosome-binding protein of the endoplasmic reticulum (ER) membrane. Studies suggest that this gene plays a role in ER proliferation, secretory pathways and secretory cell differentiation, and mediation of ER-microtubule interactions. Alternative splicing has been observed and protein isoforms are characterized by regions of N-terminal decapeptide and C-terminal heptad repeats. Splicing of the tandem repeats results in variations in ribosome-binding affinity and secretory function. The full-length nature of variants which differ in repeat length has not been determined. Pseudogenes of this gene have been identified on chromosomes 3 and 7, and RRBP1 has been excluded as a candidate gene in the cause of Alagille syndrome, the result of a mutation in a nearby gene on chromosome 20p12. [provided by RefSeq, Apr 2012]

Chromosome

20

Cytoband

p12.1

Chromosome location (bp)

17613678 - 17682295

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000125844 (version 78.38)

Entrez gene

6238

UniProt

Q9P2E9 (UniProt - Evidence at protein level)

neXtProt

NX_Q9P2E9

Antibodypedia

RRBP1 antibodies
 

PROTEIN VIEW

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RRBP1-001
 
RRBP1-002
 
RRBP1-003
 
RRBP1-005
 
RRBP1-007
 
RRBP1-201
 
RRBP1-202
 
RRBP1-203
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

RRBP1-001 ENSP00000354045
ENST00000360807
Q9P2E9
Show all »
Show » Show » 977 108.6 No 1
RRBP1-002 ENSP00000367044
ENST00000377813
F8W7S5
Show all »
Show » Show » 1410 152.5 No 1
RRBP1-003 ENSP00000381762
ENST00000398782
A2A2S5
Show all »
Show » Show » 300 31.7 No 0
RRBP1-005 ENSP00000478324
ENST00000470422
Show » 346 38.7 No 0
RRBP1-007 ENSP00000401206
ENST00000455029
F8W7S5
Show all »
Show » Show » 751 84.3 No 0
RRBP1-201 ENSP00000246043
ENST00000246043
F8W7S5
Show all »
Show » Show » 1410 152.5 No 1
RRBP1-202 ENSP00000367038
ENST00000377807
Q9P2E9
Show all »
Show » Show » 977 108.6 No 1
RRBP1-203 ENSP00000479709
ENST00000610403
F8W7S5
Show all »
Show » Show » 934 102.8 No 0