BCL2L12

GENE INFORMATION

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Gene name

BCL2L12

Synonyms

Description

BCL2-like 12 (proline rich) (HGNC Symbol)

Entrez gene summary

This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2). The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of this gene has been detected in a number of different cancers. There is a pseudogene for this gene on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

Chromosome

19

Cytoband

q13.33

Chromosome location (bp)

49665142 - 49673916

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000126453 (version 78.38)

Entrez gene

83596

UniProt

Q9HB09 (UniProt - Evidence at protein level)

neXtProt

NX_Q9HB09

Antibodypedia

BCL2L12 antibodies
 

PROTEIN VIEW

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BCL2L12-001
 
BCL2L12-002
 
BCL2L12-004
 
BCL2L12-006
 
BCL2L12-008
 
BCL2L12-009
 
BCL2L12-201
 
BCL2L12-202
 
BCL2L12-203
 
BCL2L12-204
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

BCL2L12-001 ENSP00000246785
ENST00000246785
Q9HB09
Show all »
Show » Show » 334 36.8 No 0
BCL2L12-002 ENSP00000393803
ENST00000441864
Show » 333 36.7 No 0
BCL2L12-004 ENSP00000469216
ENST00000594157
M0R1K0
Show all »
Show » 92 9.2 No 0
BCL2L12-006 ENSP00000470644
ENST00000600947
Show » 138 14.7 No 0
BCL2L12-008 ENSP00000472214
ENST00000598306
M0R1Z8
Show all »
Show » 92 10 No 0
BCL2L12-009 ENSP00000246784
ENST00000246784
Show » 250 26.9 No 0
BCL2L12-201 ENSP00000478415
ENST00000611631
I6LK00
Show all »
Show » 130 15 No 0
BCL2L12-202 ENSP00000482154
ENST00000614495
I6LJZ9
Show all »
Show » 193 21.4 No 0
BCL2L12-203 ENSP00000482218
ENST00000616144
Q9HB09
Show all »
Show » Show » 334 36.8 No 0
BCL2L12-204 ENSP00000483272
ENST00000619007
I6LJZ7
Show all »
Show » 269 29.9 No 0