PPCS

GENE INFORMATION

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Gene name

PPCS (HGNC Symbol)

Synonyms

FLJ11838

Description

Phosphopantothenoylcysteine synthetase (HGNC Symbol)

Entrez gene summary

Biosynthesis of coenzyme A (CoA) from pantothenic acid (vitamin B5) is an essential universal pathway in prokaryotes and eukaryotes. PPCS (EC 6.3.2.5), one of the last enzymes in this pathway, converts phosphopantothenate to phosphopantothenoylcysteine (Daugherty et al., 2002 [PubMed 11923312]).[supplied by OMIM, Mar 2008]

Chromosome

1

Cytoband

p34.2

Chromosome location (bp)

42456117 - 42473385

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000127125 (version 78.38)

Entrez gene

79717

UniProt

Q9HAB8 (UniProt - Evidence at protein level)

neXtProt

NX_Q9HAB8

Antibodypedia

PPCS antibodies
 

PROTEIN VIEW

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PPCS-001
 
PPCS-002
 
PPCS-003
 
PPCS-005
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PPCS-001 ENSP00000361642
ENST00000372561
Q9HAB8
Show all »
Show » Show » 311 34 No 0
PPCS-002 ENSP00000361637
ENST00000372556
Q5VVM2
Show all »
Show » 56 6.4 No 0
PPCS-003 ENSP00000361643
ENST00000372562
Q9HAB8
Show all »
Show » Show » 138 15.6 No 0
PPCS-005 ENSP00000361641
ENST00000372560
Q5VVM3
Show all »
Show » 213 22.7 No 0