GFER

GENE INFORMATION

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Gene name

GFER (HGNC Symbol)

Synonyms

ALR, ERV1, HERV1, HPO1, HPO2, HSS

Description

Growth factor, augmenter of liver regeneration (HGNC Symbol)

Entrez gene summary

The hepatotrophic factor designated augmenter of liver regeneration (ALR) is thought to be one of the factors responsible for the extraordinary regenerative capacity of mammalian liver. It has also been called hepatic regenerative stimulation substance (HSS). The gene resides on chromosome 16 in the interval containing the locus for polycystic kidney disease (PKD1). The putative gene product is 42% similar to the scERV1 protein of yeast. The yeast scERV1 gene had been found to be essential for oxidative phosphorylation, the maintenance of mitochondrial genomes, and the cell division cycle. The human gene is both the structural and functional homolog of the yeast scERV1 gene. [provided by RefSeq, Jul 2008]

Chromosome

16

Cytoband

p13.3

Chromosome location (bp)

1984207 - 1987749

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000127554 (version 78.38)

Entrez gene

2671

UniProt

P55789 (UniProt - Evidence at protein level)

neXtProt

NX_P55789

Antibodypedia

GFER antibodies
 

PROTEIN VIEW

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GFER-001
 
GFER-002
 
GFER-003
 
GFER-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GFER-001 ENSP00000248114
ENST00000248114
P55789
Show all »
Show » Show » 205 23.4 No 0
GFER-002 ENSP00000455885
ENST00000567719
H3BQQ4
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Show » Show » 130 15.4 No 0
GFER-003 ENSP00000456432
ENST00000569451
H3BRW3
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Show » 109 11.7 No 0
GFER-004 ENSP00000456189
ENST00000561710
H3BRD2
Show all »
Show » Show » 139 15.8 No 0