IGLL1

GENE INFORMATION

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Gene name

IGLL1 (HGNC Symbol)

Synonyms

14.1, CD179B, IGL5, IGLL, IGVPB

Description

Immunoglobulin lambda-like polypeptide 1 (HGNC Symbol)

Entrez gene summary

The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. This gene encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. This gene does not undergo rearrangement. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

22

Cytoband

q11.23

Chromosome location (bp)

23573125 - 23580308

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000128322 (version 78.38)

Entrez gene

3543

UniProt

P15814 (UniProt - Evidence at protein level)

neXtProt

NX_P15814

Antibodypedia

IGLL1 antibodies
 

PROTEIN VIEW

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IGLL1-001
 
IGLL1-002
 
IGLL1-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

IGLL1-001 ENSP00000329312
ENST00000330377
P15814
Show all »
Show » Show » 213 23 No 0
IGLL1-002 ENSP00000249053
ENST00000249053
P15814
Show all »
Show » Show » 84 8.6 No 0
IGLL1-003 ENSP00000403391
ENST00000438703
C9JEE0
Show all »
Show » Show » 180 19.2 No 0