HOXD3

GENE INFORMATION

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Gene name

HOXD3 (HGNC Symbol)

Synonyms

HOX1D, HOX4, HOX4A

Description

Homeobox D3 (HGNC Symbol)

Entrez gene summary

This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that removed the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. The protein encoded by this gene may play a role in the regulation of cell adhesion processes. [provided by RefSeq, Jul 2008]

Chromosome

2

Cytoband

q31.1

Chromosome location (bp)

176136612 - 176173102

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000128652 (version 78.38)

Entrez gene

3232

UniProt

P31249 (UniProt - Evidence at protein level)

neXtProt

NX_P31249

Antibodypedia

HOXD3 antibodies
 

PROTEIN VIEW

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HOXD3-001
 
HOXD3-002
 
HOXD3-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HOXD3-001 ENSP00000249440
ENST00000249440
P31249
Show all »
Show » Show » 432 45.7 No 0
HOXD3-002 ENSP00000392615
ENST00000432796
C9J1M3
Show all »
Show » 100 10.5 No 0
HOXD3-004 ENSP00000386498
ENST00000410016
P31249
Show all »
Show » Show » 432 45.7 No 0