CGNL1

GENE INFORMATION

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Gene name

CGNL1 (HGNC Symbol)

Synonyms

FLJ14957, JACOP, KIAA1749, paracingulin

Description

Cingulin-like 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the cingulin family. The encoded protein localizes to both adherens and tight cell-cell junctions and mediates junction assembly and maintenance by regulating the activity of the small GTPases RhoA and Rac1. Heterozygous chromosomal rearrangements resulting in association of the promoter for this gene with the aromatase gene are a cause of aromatase excess syndrome. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Nov 2011]

Chromosome

15

Cytoband

q21.3

Chromosome location (bp)

57375967 - 57550727

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000128849 (version 78.38)

Entrez gene

84952

UniProt

Q0VF96 (UniProt - Evidence at protein level)

neXtProt

NX_Q0VF96

Antibodypedia

CGNL1 antibodies
 

PROTEIN VIEW

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CGNL1-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CGNL1-001 ENSP00000281282
ENST00000281282
Q0VF96
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