KLK10

GENE INFORMATION

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Gene name

KLK10 (HGNC Symbol)

Synonyms

NES1, PRSSL1

Description

Kallikrein-related peptidase 10 (HGNC Symbol)

Entrez gene summary

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]

Chromosome

19

Cytoband

q13.41

Chromosome location (bp)

51012739 - 51020175

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000129451 (version 78.38)

Entrez gene

5655

UniProt

O43240 (UniProt - Evidence at protein level)

neXtProt

NX_O43240

Antibodypedia

KLK10 antibodies
 

PROTEIN VIEW

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KLK10-001
 
KLK10-002
 
KLK10-004
 
KLK10-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KLK10-001 ENSP00000311746
ENST00000309958
O43240
Show all »
Show » Show » 276 30.2 Yes 0
KLK10-002 ENSP00000351640
ENST00000358789
O43240
Show all »
Show » Show » 276 30.2 Yes 0
KLK10-004 ENSP00000471610
ENST00000599077
M0R132
Show all »
Show » Show » 143 15.7 Yes 0
KLK10-201 ENSP00000375681
ENST00000391805
O43240
Show all »
Show » Show » 276 30.2 Yes 0